Protein Alignment CG18747 and Txnip

DIOPT Version :10

• Sequence 1: NP_652650.2
• Gene: CG18747 / 59143
• FlyBaseID: FBgn0042104
• Length: 418
• Species: Drosophila melanogaster
• Sequence 2: NP_001008767.1
• Gene: Txnip / 117514
• RGDID: 620886
• Length: 394
• Species: Rattus norvegicus
• Alignment Length: 372
• Identity: 83/372 - (22%)
• Similarity: 154/372 - (41%)
• Gaps: 44/372 - (11%)

  Fly     6 EISFDNNKHGTFYAGQLVKGCATLKCDRSKEVQAVLLKVVGYSITKWSEKSLGSTKLYVGREDYL 70
            |:.| |:....:.:|:.|.|..|::......|:||.:...|.:...|.:.|....:..    |||
  Rat    11 EVVF-NDPEKVYGSGEKVAGRVTVEVCEVTRVKAVRILACGVAKVLWMQGSQQCKQTL----DYL 70

  Fly    71 S-SNTYLVGSEQNNTHNNTHRLTIEAGVHSYNFTCQLPYQCP--SSFEGRHGCIRYIVKVLLIRP 132
            . .:|.|:  |...|..|...:......:.|.|..:|| |.|  :||:|::||:.|.||..|.||
  Rat    71 RYEDTLLL--EDQPTGENEMVIMRPGNKYEYKFGFELP-QGPLGTSFKGKYGCVDYWVKAFLDRP 132

  Fly   133 WKFDQAYTKGFTVLKMLDLNFDTPQLKSAAHSEGYRTFCCGPCKTDPLKLELHLPQAGYVPGQKI 197
            .:..|...|.|.|:.::|:|  ||.|.:...::..:...|.......:.:...:.:.|:..|..|
  Rat   133 SQPTQEAKKNFEVMDLVDVN--TPDLMAPVSAKKEKKVSCMFIPDGRVSVSARIDRKGFCEGDDI 195

  Fly   198 PV--------TIVVVNNTAVAVSEIRLSLVMLVRYYSVSPEHSRVERLIISRAKGESVLK-QCTR 253
            .:        :.:||...|:           :.|:..::...::|....:|..:|..::. .|..
  Rat   196 SIHADFENTCSRIVVPKAAI-----------VARHTYLANGQTKVLTQKLSSVRGNHIISGTCAS 249

  Fly   254 SQTIDLPVPSTPPTCVELSNLIQIAYQLEVEALVKSLREQQLMVMPVTVGTIPLAVSGIVVQQPP 318
            .:...|.|....|:.:. .|::::.|.|.:...|.. .::.::.:|:.:|: ...:|........
  Rat   250 WRGKSLRVQKIRPSILG-CNILRVEYSLLIYVSVPG-SKKVILDLPLVIGS-RSGLSSRTSSMAS 311

  Fly   319 RRSAHYEG-----PDSRRNPP---DELPMVTALESLPSDLASSAADS 357
            |.|:....     ||:...||   |.:|....|||..:.|.....||
  Rat   312 RTSSEMSWIDLNIPDTPEAPPCYMDVIPEDHRLESPTTPLLDDVDDS 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18747	NP_652650.2	Arrestin_N	5..152	CDD:425619	43/148 (29%)
		Arrestin_C	176..307	CDD:214976	20/139 (14%)
Txnip	NP_001008767.1	Arrestin_N	10..152	CDD:451447	43/148 (29%)
		Arrestin_C	174..298	CDD:460676	19/136 (14%)