DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18746 and arrdc2

DIOPT Version :9

Sequence 1:	NP_652649.1	Gene:	CG18746 / 59142	FlyBaseID:	FBgn0042103	Length:	438	Species:	Drosophila melanogaster
Sequence 2:	XP_012821263.1	Gene:	arrdc2 / 780156	XenbaseID:	XB-GENE-946088	Length:	418	Species:	Xenopus tropicalis

Alignment Length:	441	Identity:	102/441 - (23%)
Similarity:	177/441 - (40%)	Gaps:	99/441 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 IFYAGQLISGQVVIKTEKEKSVKAVILNIKGYAETHWADTEHDPDDQSNG-----ESFNGHVDYL 74
            ::.||:::.|:||::..||..|.|:.:..:|.|..||.::      :|.|     ..|..:..||
Frog    38 VYSAGEIVEGKVVLELCKELRVSALEVCGRGLATVHWLES------RSVGMNTVYSDFTSYETYL 96

  Fly    75 ATRAYLHGSSSSIEVLIEPGTSSYRFACQLPITCPSSFEGTLGRIRYLVNVRFVRPWKFDLNFNR 139
            ..|.:|...:.:: .::..|...:.|:.|||.|..:||||..|.:||.|..:..|||.......:
Frog    97 RKRQHLIRDNGTL-TMLPAGRHEFPFSFQLPETLVTSFEGKHGSVRYWVKAKLHRPWCTVKKVKK 160

  Fly   140 CFTVIKVMDLNSESLMLRVPSQVESQRTFCCFPCRSSPLSMRLSVPQSGFVPGQIVPVEVMVSND 204
            .||||:.:|:|:..|:  .|.....::....:.|....:|:...:.:.|:.||:::|:...:.|.
Frog   161 EFTVIEPIDINTPDLL--APQAGSKEKIAHAWYCNLGHVSVTAKIDRKGYTPGEVIPIFAEIDNC 223

  Fly   205 SGVAVEDITVKLTMVVIYYSQPPSADTNKDRFEMVLKTGGGVSTKCRQQFTFD---LKVPPTPPT 266
            :..||      :....|..||...|.....:.:.|:.|..|.:....::.|:.   ||:||..|:
Frog   224 TTRAV------IPKAAIIQSQAFVARGTMKQKKSVVATLAGDAVPAGKRETWHGRALKIPPLGPS 282

  Fly   267 CFNLCSIIQIGYQVEAEARVKGCHGGQSLHMPITIGSVPL------TKQLQKEPRT---WGEVLP 322
            ... |.||::.|.::....:.| .....|.:|:.||::||      |..:..:...   |..:..
Frog   283 ILQ-CRIIRVEYTLKVCVEIPG-SSNLVLELPLVIGTIPLHPFGSRTSSVGSQYSVNLEWLRMTV 345

  Fly   323 PQQLDAKALILIGSEQNGEALGSPNPWAADPSIAPPSYA------EAKHISPDPHKFSKSKKKSQ 381
            |:|                    |.|        ||.|:      ||:|....||..|..
Frog   346 PEQ--------------------PEP--------PPDYSSVVSEEEAEHNLSPPHHSSMG----- 377

  Fly   382 KRGVKGSQERKAETIVFSPLYAVFD--------LSNQVDEMTLRANEPKTD 424
                         .::..|.||...        |.::||     .|.|..|
Frog   378 -------------CLLEGPFYAYIQEFRNRPPPLYSEVD-----PNPPTAD 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18746	NP_652649.1	Arrestin_N	4..150	CDD:278754	42/139 (30%)
CG18746	NP_652649.1	Arrestin_C	174..306	CDD:214976	30/134 (22%)
arrdc2	XP_012821263.1	Arrestin_N	36..171	CDD:334019	42/139 (30%)
arrdc2	XP_012821263.1	Arrestin_C	195..320	CDD:214976	30/132 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	85	1.000	Domainoid score	I8042
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	151	1.000	Inparanoid score	I4245
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D311636at33208
OrthoFinder	1	1.000	-	-		FOG0000089
OrthoInspector	1	1.000	-	-		mtm9421
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X122
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.970