DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18746 and Arrdc2

DIOPT Version :9

Sequence 1:	NP_652649.1	Gene:	CG18746 / 59142	FlyBaseID:	FBgn0042103	Length:	438	Species:	Drosophila melanogaster
Sequence 2:	NP_081836.1	Gene:	Arrdc2 / 70807	MGIID:	1918057	Length:	407	Species:	Mus musculus

Alignment Length:	376	Identity:	84/376 - (22%)
Similarity:	159/376 - (42%)	Gaps:	54/376 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 SQGIFYAGQLISGQVVIKTEKEKSVKAVILNIKGYAETHWADTEHDPDDQSNGESFNGHVDYLAT 76
            ::.:|:.||.::|:|:::......|.|:.|..:|.|..||.::.......:..:|::..|:.:..
Mouse    20 TEPVFHGGQAVAGRVLLELAGAARVGALRLRARGRARAHWTESRSAGSSTAYTQSYSERVEVVNH 84

  Fly    77 RAYLHGSSSSIEVLIEPGTSSYRFACQLPITCPSSFEGTLGRIRYLVNVRFVRPWKFDLNFNRCF 141
            ||.|....|.....:..|...:.|:.||||:..:||||..|.:||.:.....|||.......:.|
Mouse    85 RATLLAPDSGDIATLPAGRHEFPFSFQLPISLVTSFEGKHGSVRYSIKATLHRPWVPARCARKVF 149

  Fly   142 TVIKVMDLNSESLMLRVPSQVESQRTFCCFPCRSSPLSMRLSVPQSGFVPGQIVPVEVMVSNDSG 206
            |||:.:|:|:.:|:  .|.....::....:.|....:|:...:.:.|:.||:::|:...:.|.|.
Mouse   150 TVIEPVDINTPALL--EPQAGAREKVARSWYCTRGLVSLSAKIDRKGYTPGEVIPIFAEIDNGST 212

  Fly   207 VAVEDITVKLTMVVIYYSQPPSADTNKDRFEMVLKTGGGVSTKCRQQFTFD---LKVPPTPPTCF 268
            .||:      ....:..:|...|...:.:...|:.:..|......::..:.   |::||..|:..
Mouse   213 RAVQ------PRAALVQTQTFMARGARKQKRAVVASVDGEPVGPNRRALWPGRALRIPPVGPSIL 271

  Fly   269 NLCSIIQIGYQVEAEARVKGCHGGQSLHMPITIGSVPLTKQLQKEPRTWGEVLPPQQLDAKALIL 333
            . |.::.:.|.::....:.| .....|.:|:.||:|||      .|
Mouse   272 Q-CRVLSVDYSLKVFVDIPG-SSKLLLELPLVIGTVPL------HP------------------- 309

  Fly   334 IGSEQNGEALGSPNPWAADPSI--------APPSYAEAKH------ISPDP 370
            :||  ...::||...:..|..:        |||.|:|...      .||.|
Mouse   310 LGS--RSASVGSRASFLQDWGLCTMMDRPEAPPEYSEVVRESQLVCASPGP 358

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18746	NP_652649.1	Arrestin_N	4..150	CDD:278754	39/137 (28%)
CG18746	NP_652649.1	Arrestin_C	174..306	CDD:214976	25/134 (19%)
Arrdc2	NP_081836.1	Arrestin_N	9..158	CDD:278754	39/137 (28%)
Arrdc2	NP_081836.1	Arrestin_C	180..307	CDD:214976	25/134 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	96	1.000	Domainoid score	I7292
eggNOG	1	0.900	-	-		E1_KOG3780
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	145	1.000	Inparanoid score	I4409
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D311636at33208
OrthoFinder	1	1.000	-	-		FOG0000089
OrthoInspector	1	1.000	-	-		otm42766
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X122
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.870