Protein Alignment CG18746 and ARRDC5

DIOPT Version :9

• Sequence 1: NP_652649.1
• Gene: CG18746 / 59142
• FlyBaseID: FBgn0042103
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_001354118.1
• Gene: ARRDC5 / 645432
• HGNCID: 31407
• Length: 350
• Species: Homo sapiens
• Alignment Length: 403
• Identity: 74/403 - (18%)
• Similarity: 143/403 - (35%)
• Gaps: 93/403 - (23%)

  Fly     2 VICEIEFCNNSQGIFYAGQLISGQVVI---KTEKEKSVKAVILNIKGYAETHWADTEHDPDDQSN 63
            |:..||.......|:.||..|.|||::   .|..:..||..::. :||.|  |::......|.|.
Human     3 VVKSIELVLPEDRIYLAGSSIKGQVILTLNSTLVDPIVKVELVG-RGYVE--WSEEAGASCDYSR 64

  Fly    64 GESFNGHVDYL-ATRAYLHGSSSSIEVL-----------IEPGTSSYRFACQLPI------TCPS 110
            ....|...||: .|:.:.....:|..|.           ::|.:.:::.:..|.:      ..||
Human    65 NVICNNKADYVHKTKTFPVEEMASRSVTQAGVQWHDLGSLQPPSRTFKLSSHLSLLSTWNYRLPS 129

  Fly   111 SFEGTLGRIRYLVNVRFVRPWKFDLNFNRCFTVIKVMDLNSESLMLRVPSQVESQRTFCCFPCRS 175
            :|....|.:.|.|....:.. :..|...|.:.:::......:....:.|..||::.......||.
Human   130 TFTSKFGHVFYFVQASCMGR-EHILAKKRMYLLVQGTSTFHKETPFQNPLFVEAEEKVSYNCCRQ 193

  Fly   176 SPLSMRLSVPQSGFVPGQIVPVEVMVSNDSGVAVEDITVKLTMVVIYYSQPPSADTNKDRFEMVL 240
            ..:.:::.:.::.|.||:.|.....::|.:...::.:...|...:.|....|||: .:.|.:.
Human   194 GTVCLQIQMERNTFTPGEKVVFTTEINNQTSKCIKTVVFALYAHIQYEGFTPSAE-RRSRLDS-- 255

  Fly   241 KTGGGVSTKCRQQFTFDLKVPPTPPTCFNLCSIIQIGYQVEAEARVKGCHGGQSLHMPITIGSVP 305
                  |...||:..       ||.|.||...::                  .:.::|:.:....
Human   256 ------SELLRQEAN-------TPVTRFNTTKVV------------------STFNLPLLLSVSS 289

  Fly   306 LTKQLQKEPRTWGEVLPPQ--------------QLDAKALILIGSEQNGEALGSPNPWAADPSIA 356
            .|:.        ||::..:              .|.||..|:|.|.            :.|.:|.
Human   290 STQD--------GEIMHTRYELVTTVHLPWSLTSLKAKVPIIITSA------------SVDSAIC 334

  Fly   357 PPSYAEAKHISPD 369
            ..|......::||
Human   335 QLSEDGVLPVNPD 347

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18746	NP_652649.1	Arrestin_N	4..150	CDD:278754	34/166 (20%)
		Arrestin_C	174..306	CDD:214976	21/131 (16%)
ARRDC5	NP_001354118.1	Arrestin_N	13..146	CDD:328947	30/135 (22%)
		Arrestin_C	192..326	CDD:308405	29/175 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145963
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D817924at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11188
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.950