Protein Alignment CG18746 and Arrdc3

DIOPT Version :10

• Sequence 1: NP_652649.1
• Gene: CG18746 / 59142
• FlyBaseID: FBgn0042103
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_001007798.1
• Gene: Arrdc3 / 309945
• RGDID: 1359478
• Length: 414
• Species: Rattus norvegicus
• Alignment Length: 416
• Identity: 98/416 - (23%)
• Similarity: 178/416 - (42%)
• Gaps: 57/416 - (13%)

  Fly     9 CNNSQG--IFYAGQLISGQVVIKTEKEKSVKAVILNIKGYAETHWADTEHDPDDQSNGESFNGHV 71
            |.|...  ::.:|..:||:|.::...|..||::.::.:|:|:..|.::.:...:.:..:::...|
  Rat    15 CLNDSNVPVYSSGDTVSGRVNLEVTGEIRVKSLKIHARGHAKVRWTESRNAGSNTAYTQNYTEEV 79

  Fly    72 DYLATRAYLHGSSSSIE------VLIEPGTSSYRFACQLPIT-CPSSFEGTLGRIRYLVNVRFVR 129
            :|...:..|.|.....:      ..|..|...|.|:.:||.| ..:||||..|.:||.|.....|
  Rat    80 EYFNHKDILIGHERDDDNCEEGFSTIHSGRHEYAFSFELPQTPLATSFEGRHGSVRYWVKAELHR 144

  Fly   130 PWKFDLNFNRCFTVIKVMDLNSESLMLRVPSQVESQRTFCCFPCRSSPLSMRLSVPQSGFVPGQI 194
            ||...:...:.|||.:.:|:|:.||:  .|.....::|.||:.|.|.|:|:...:.:.|:.||:.
  Rat   145 PWLLPVKLKKEFTVFEHIDINTPSLL--SPQAGTKEKTLCCWFCTSGPISLSAKIERKGYTPGES 207

  Fly   195 VPVEVMVSNDSGVAVEDITVKLTMVVIYYSQPPSADTNKDRFEMVLKTGGGVSTKCRQQFTFD-- 257
            :.:...:.|.|...|      :....||.:|...|.......:.::....|.|....:..|:|
  Rat   208 IQIFAEIENCSSRMV------VPKAAIYQTQAFYAKGKMKEVKQLVANLRGESLSSGKTETWDGK 266

  Fly   258 -LKVPPTPPTCFNLCSIIQIGYQVEAEARVKGCHGGQSLHMPITIGSVPL------TKQLQKE-- 313
             ||:||..|:..: ||||::.|.:.....:.|.. ...|.:|:.||::||      |..:..:
  Rat   267 LLKIPPVSPSILD-CSIIRVEYSLMVYVDIPGAM-DLLLSLPLVIGTIPLHPFGSRTSSVSSQCS 329

  Fly   314 ----------------PRTWGEVLPPQQLDAKALILIGSEQNGEALGSP-----NPWAADPSIAP 357
                            |.::.||:..:|.......:...:....||..|     ..:...|   |
  Rat   330 MNMNWLGLSLPERPEAPPSYAEVVTEEQRRNNLAPVSACDDFERALQGPLFAYIQEFRFLP---P 391

  Fly   358 PSYAEAKHISPDPHKFSKSKKKSQKR 383
            |.|:|   |.|:|.:.|:.:.....|
  Rat   392 PLYSE---IDPNPDQSSEDRPSCPSR 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18746	NP_652649.1	Arrestin_N	4..150	CDD:425619	38/149 (26%)
		Arrestin_C	174..306	CDD:214976	32/134 (24%)
Arrdc3	NP_001007798.1	Arrestin_N	22..165	CDD:425619	36/142 (25%)
		Arrestin_C	187..314	CDD:214976	32/134 (24%)
		PPxY motif 1. /evidence=ECO:0000305	346..349		1/2 (50%)
		PPxY motif 2. /evidence=ECO:0000305	391..394		2/2 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	393..414		6/23 (26%)