Protein Alignment CG18746 and ARRDC2

DIOPT Version :9

• Sequence 1: NP_652649.1
• Gene: CG18746 / 59142
• FlyBaseID: FBgn0042103
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_056498.1
• Gene: ARRDC2 / 27106
• HGNCID: 25225
• Length: 407
• Species: Homo sapiens
• Alignment Length: 397
• Identity: 90/397 - (22%)
• Similarity: 164/397 - (41%)
• Gaps: 65/397 - (16%)

  Fly    15 IFYAGQLISGQVVIKTEKEKSVKAVILNIKGYAETHWADTEHDPDDQSNGESFNGHVDYLATRAY 79
            :|..||.::|:|:::......|.|:.|..:|.|..||.::.......:..:|::..|:.::.||.
Human    23 VFSGGQAVAGRVLLELSSAARVGALRLRARGRAHVHWTESRSAGSSTAYTQSYSERVEVVSHRAT 87

  Fly    80 LHGSSSSIEVLIEPGTSSYRFACQLPITCPSSFEGTLGRIRYLVNVRFVRPWKFDLNFNRCFTVI 144
            |....:.....:.||...:.|:.|||.|..:||||..|.:||.:.....|||.......:.||||
Human    88 LLAPDTGETTTLPPGRHEFLFSFQLPPTLVTSFEGKHGSVRYCIKATLHRPWVPARRARKVFTVI 152

  Fly   145 KVMDLNSESLMLRVPSQVESQRTFCCFPCRSSPLSMRLSVPQSGFVPGQIVPVEVMVSNDSGVAV 209
            :.:|:|:.:|:  .|.....::....:.|....:|:...:.:.|:.||:::||...:.|.|...|
Human   153 EPVDINTPALL--APQAGAREKVARSWYCNRGLVSLSAKIDRKGYTPGEVIPVFAEIDNGSTRPV 215

  Fly   210 EDITVKLTMVVIYYSQPPSADTNKDRFEMVLKTGGGVSTKCRQQFTFD---LKVPPTPPTCFNLC 271
                  |....:..:|...|...:.:...|:.:..|......|:..:.   |::||..|:..: |
Human   216 ------LPRAAVVQTQTFMARGARKQKRAVVASLAGEPVGPGQRALWQGRALRIPPVGPSILH-C 273

  Fly   272 SIIQIGYQVEAEARVKGCHGGQSLHMPITIGSVPL---------------------TKQLQKEPR 315
            .::.:.|.::....:.|. ....|.:|:.||::||                     ...|.:.|.
Human   274 RVLHVDYALKVCVDIPGT-SKLLLELPLVIGTIPLHPFGSRSSSVGSHASFLLDWRLGALPERPE 337

  Fly   316 TWGEVLPPQQLDAKALILIGSEQNGEALG-SPNPWAADPSIA----------------PPSYAEA 363
            .     ||:..:..|      :....||| ||.|...||.::                ||.|:|.
Human   338 A-----PPEYSEVVA------DTEEAALGQSPFPLPQDPDMSLEGPFFAYIQEFRYRPPPLYSEE 391

  Fly   364 KHISPDP 370
               .|:|
Human   392 ---DPNP 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18746	NP_652649.1	Arrestin_N	4..150	CDD:278754	39/134 (29%)
		Arrestin_C	174..306	CDD:214976	26/134 (19%)
ARRDC2	NP_056498.1	Arrestin_N	9..158	CDD:278754	39/134 (29%)
		Arrestin_C	181..307	CDD:214976	26/133 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	95	1.000	Domainoid score	I7402
eggNOG	1	0.900	-	-		E1_KOG3780
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	146	1.000	Inparanoid score	I4428
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D311636at33208
OrthoFinder	1	1.000	-	-		FOG0000089
OrthoInspector	1	1.000	-	-		mtm8525
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X122
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	9	8.870