DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18746 and arrd-12

DIOPT Version :9

Sequence 1:	NP_652649.1	Gene:	CG18746 / 59142	FlyBaseID:	FBgn0042103	Length:	438	Species:	Drosophila melanogaster
Sequence 2:	NP_001309576.1	Gene:	arrd-12 / 187636	WormBaseID:	WBGene00011053	Length:	186	Species:	Caenorhabditis elegans

Alignment Length:	169	Identity:	52/169 - (30%)
Similarity:	80/169 - (47%)	Gaps:	15/169 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 IFYAGQLISGQVVIKTEKEKSVKAVILNIKGYAETHWADTEHDPDDQSNGES-FNGH-VDYLATR 77
            ::.|||.|||:||..|..:::.:.:.:.:.|.:.|.:...|.:....|.||| ...| |.|.||.
Worm    14 VYAAGQKISGRVVFSTASQQNPRWIDVQLHGRSHTFFTRQESETKTNSKGESETKTHTVHYTATA 78

  Fly    78 AYL-------HGSSSSIEVLIEPGTSSYRFACQLPIT-CPSSFEGTLGRIRYLVNVRFVRPWKFD 134
            .:|       ..:..:..:|  ||...::|..|||.: .|.||||..|.|||.|.....|.|||:
Worm    79 KHLDTAVPLWRKTDKAARLL--PGKYEWQFWFQLPCSVLPPSFEGNNGNIRYWVRAEVSRSWKFN 141

  Fly   135 LNFNRCFTVIKVMDLNSESLMLRVPSQVESQRTF--CCF 171
            :.....|.:...:|||:..: .|.|....:.:..  |||
Worm   142 IVDESSFEIAPFLDLNTMPI-ARTPLDGFAVKNLGCCCF 179

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18746	NP_652649.1	Arrestin_N	4..150	CDD:278754	45/144 (31%)
CG18746	NP_652649.1	Arrestin_C	174..306	CDD:214976
arrd-12	NP_001309576.1	Arrestin_N	6..157	CDD:389964	45/144 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	95	1.000	Domainoid score	I4648
eggNOG	1	0.900	-	-		E1_KOG3780
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H119234
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D311636at33208
OrthoFinder	1	1.000	-	-		FOG0000089
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.820