DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18746 and arrd-6

DIOPT Version :9

Sequence 1:	NP_652649.1	Gene:	CG18746 / 59142	FlyBaseID:	FBgn0042103	Length:	438	Species:	Drosophila melanogaster
Sequence 2:	NP_001254290.1	Gene:	arrd-6 / 185541	WormBaseID:	WBGene00009579	Length:	469	Species:	Caenorhabditis elegans

Alignment Length:	473	Identity:	95/473 - (20%)
Similarity:	180/473 - (38%)	Gaps:	106/473 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 SQGIFYAGQLISGQVVIKTEKEKSVKAVILNIKGYAETH-------WADTEHDPDDQSNGESFNG 69
            ::.::|||:.|||.|:::..:...::.:.:.::|  :.|       ..:.....|||.
Worm    39 NKDVYYAGETISGSVLLENTENIKIRGIRVLLRG--KVHATLKVVKSGERRTLKDDQY------- 94

  Fly    70 HVDYLATRAYLHG-----SSSSIEVLIEPGTSSYRFACQLP-ITCPSSFEGTLGRIRYLVNVRFV 128
               .|..:..|.|     .|.|:.:|.. |...:.|...|| .:.|.|.|.....|||...|...
Worm    95 ---VLDEKQLLWGKDKSDESDSVPILAR-GVHQFSFNFDLPQSSLPCSLESRHCTIRYYFKVIID 155

  Fly   129 RPWKFDLNFNRCFTVI-KVMDLNSESLMLRVPSQVESQRTFCCFPCRSSPLSMRLSVPQSGFVPG 192
            .|:.......:.||:| ..:|...|..:  .|...:.::..||:.|:...|::|:.:.::.:|.|
Worm   156 IPYASSPQGIKYFTIIGPHIDSMEEKYL--SPLSAQDRKVNCCWCCQRGALALRIILERTAYVCG 218

  Fly   193 QIVPVEVMVSNDSGVA-------VEDITV-----------KLTMVVIYYSQPPSADTNKDRFEMV 239
            :.:.|...:.|....|       |:.:.|           .::.||..:..|..|..::.:::..
Worm   219 ENIRVRAQIENRQSTAQSLVIRLVQHVEVFVEKGLLGENKMMSCVVFEHKSPAIAANSQGKYDST 283

  Fly   240 LKTGGGVSTKCRQQFTFDLKVPPTPPTCFNLCSIIQIGYQVEAEARVKGC----HGGQSLHM--P 298
            |:.              .:::|..|||...:|.:|||.|.:..      |    .|.:.||:  |
Worm   284 LEQ--------------PIRLPVVPPTLVGVCRLIQIYYALRV------CMEDEKGNECLHIDFP 328

  Fly   299 ITIGSVPLTKQLQKEPRTWGEVLPPQQLD-----------AKALILIGSEQNGEALGSPNPWAAD 352
            :|:.::|.  ::...|.      ||...|           ......:|...:||  |.......:
Worm   329 LTVATIPY--RIPNAPP------PPVDYDFCSNHVEGGKYVSPEFRLGQVYDGE--GEEINKEEE 383

  Fly   353 PSIAPPSYAE-------AKHISPD--PHKFSKSKKKSQKRGVKGSQERKAETIVFS-PLYAVFDL 407
            ..:..|.|.:       :.|:|.|  ...|::....|.....:.:..|:...:|.| |..|:.|.
Worm   384 IVLYRPVYVKLADRRIGSPHVSKDFRSGSFTRIADSSLALVTEPNGSRRRSILVASNPCLAMRDE 448

  Fly   408 SNQVDEMTLRANEPKTDG 425
            |  :||..:..|...::|
Worm   449 S--MDEKLMMTNGCNSEG 464

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18746	NP_652649.1	Arrestin_N	4..150	CDD:278754	34/151 (23%)
CG18746	NP_652649.1	Arrestin_C	174..306	CDD:214976	29/155 (19%)
arrd-6	NP_001254290.1	Arrestin_N	34..174	CDD:278754	33/147 (22%)
arrd-6	NP_001254290.1	Arrestin_C	201..336	CDD:214976	29/154 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D311636at33208
OrthoFinder	1	1.000	-	-		FOG0000089
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920