DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18746 and arrd-10

DIOPT Version :9

Sequence 1:	NP_652649.1	Gene:	CG18746 / 59142	FlyBaseID:	FBgn0042103	Length:	438	Species:	Drosophila melanogaster
Sequence 2:	NP_001364600.1	Gene:	arrd-10 / 174936	WormBaseID:	WBGene00010268	Length:	401	Species:	Caenorhabditis elegans

Alignment Length:	374	Identity:	59/374 - (15%)
Similarity:	122/374 - (32%)	Gaps:	121/374 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 HVDYLATRAYLHGSSSSIEVLIEPGTSSYRFACQLPITCPSSFEGTLGRI--RYLVNVRFVRPWK 132
            |:.:.|.:.   .::..|:|:.| |.........:|...|.:|.|..|.|  |:|:.::..|...
Worm    66 HIPFTAIQL---PTTKGIDVIPE-GHHRLPIFLNVPHHMPGTFNGKFGAIVYRFLIKLKVKRFSS 126

  Fly   133 FDLNFNRCFTVIKVMDLNSESLMLRVPSQVESQRTFCCFPCRSSPLS------------------ 179
            .|.....|...:.|:...|          :|.|.:|      :.|:|
Worm   127 GDEGTIECEKAVDVLGRIS----------LEQQPSF------AQPVSIDRHVKKKAFFMNRLEAH 175

  Fly   180 MRLSVPQSGFVPGQIVPVEVMVSNDS-GVAVEDITVKLTMVVIYYSQPPSADTNKDRFEMVLKTG 243
            ::..:.::.:..|..:.|...:.|:. ...::.:.::|...::|    .|.|..:....::.:..
Worm   176 IKFEIERAAYSVGDHILVTGEIKNEHLSNPIKHVALELRQHILY----ASGDAQRSDTRLITRLI 236

  Fly   244 GGVSTKCRQQFTFDLKVPPT-----------PPTCFNLCSIIQIGYQVEAEARV----KGCHGGQ 293
            .|             .||||           |..|:.  |::..|..|:....:    .||.
Worm   237 LG-------------SVPPTETFAVFHSFQVPFDCYP--SLVWNGNPVQVTYELLLTNSGCF--- 283

  Fly   294 SLHMPITIGS------------VPLTKQLQKEPRTWGEVLPPQQLDAKALILIGSEQNGEALGSP 346
            .:..|:.:|:            .|.:...:..|.|....:||.::....              .|
Worm   284 EIGTPVFLGNYGSPNSTRRSIMYPESTSGEAPPSTTYYCVPPSEMSFTV--------------DP 334

  Fly   347 NPWA-----ADPSIAP------------PSYAEAKHISPDPHKFSKSKK 378
            .|::     .||...|            |:|...::..|..:.|:.:::
Worm   335 PPYSTFGAKTDPVFIPIHMLKTPYRPFAPAYHMFRNHGPPKYDFNSNQR 383

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18746	NP_652649.1	Arrestin_N	4..150	CDD:278754	18/81 (22%)
CG18746	NP_652649.1	Arrestin_C	174..306	CDD:214976	23/177 (13%)
arrd-10	NP_001364600.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3780
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11188
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910