Protein Alignment CG18746 and Arrdc3

DIOPT Version :10

• Sequence 1: NP_652649.1
• Gene: CG18746 / 59142
• FlyBaseID: FBgn0042103
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_001036056.1
• Gene: Arrdc3 / 105171
• MGIID: 2145242
• Length: 414
• Species: Mus musculus
• Alignment Length: 417
• Identity: 102/417 - (24%)
• Similarity: 184/417 - (44%)
• Gaps: 59/417 - (14%)

  Fly     9 CNNSQG--IFYAGQLISGQVVIKTEKEKSVKAVILNIKGYAETHWADTEHDPDDQSNGESFNGHV 71
            |.|...  ::.:|..:||:|.::...|..||::.::.:|:|:..|.::.:...:.:..:::...|
Mouse    15 CLNDSNVPVYSSGDTVSGRVNLEVTGEIRVKSLKIHARGHAKVRWTESRNAGSNTAYTQNYTEEV 79

  Fly    72 DYLATRAYLHG----SSSSIEVL--IEPGTSSYRFACQLPIT-CPSSFEGTLGRIRYLVNVRFVR 129
            :|...:..|.|    ..:|.|..  |..|...|.|:.:||.| ..:||||..|.:||.|.....|
Mouse    80 EYFNHKDILIGHERDDDNSEEGFHTIHSGRHEYAFSFELPQTPLATSFEGRHGSVRYWVKAELHR 144

  Fly   130 PWKFDLNFNRCFTVIKVMDLNSESLMLRVPSQVESQRTFCCFPCRSSPLSMRLSVPQSGFVPGQI 194
            ||...:...:.|||.:.:|:|:.||:  .|.....::|.||:.|.|.|:|:...:.:.|:.||:.
Mouse   145 PWLLPVKLKKEFTVFEHIDINTPSLL--SPQAGTKEKTLCCWFCTSGPISLSAKIERKGYTPGES 207

  Fly   195 VPVEVMVSNDSGVAVEDITVKLTMVVIYYSQPPSADTNKDRFEMVLKTGGGVSTKCRQQFTFD-- 257
            :.:...:.|.|...|      :....||.:|...|.......:.::....|.|....:..|::
Mouse   208 IQIFAEIENCSSRMV------VPKAAIYQTQAFYAKGKMKEVKQLVANLRGESLSSGKTETWNGK 266

  Fly   258 -LKVPPTPPTCFNLCSIIQIGYQVEAEARVKGCHGGQSLHMPITIGSVPL------TKQLQKE-- 313
             ||:||..|:..: ||||::.|.:.....:.|.. ...|.:|:.||::||      |..:..:
Mouse   267 LLKIPPVSPSILD-CSIIRVEYSLMVYVDIPGAM-DLLLSLPLVIGTIPLHPFGSRTSSVSSQCS 329

  Fly   314 ----------------PRTWGEVLPPQQLDAKALILIGSEQNGE-ALGSP-----NPWAADPSIA 356
                            |.::.||:..:| ....|..:|:..:.| ||..|     ..:...|
Mouse   330 MSMNWLALALPERPEAPPSYAEVVTEEQ-RRNNLAPVGACDDFERALQGPLFAYIQEFRFLP--- 390

  Fly   357 PPSYAEAKHISPDPHKFSKSKKKSQKR 383
            ||.|:|   |.|:|.:.|:.:.....|
Mouse   391 PPLYSE---IDPNPDQSSEDRPSCPSR 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18746	NP_652649.1	Arrestin_N	4..150	CDD:425619	40/149 (27%)
		Arrestin_C	174..306	CDD:214976	31/134 (23%)
Arrdc3	NP_001036056.1	Arrestin_N	22..165	CDD:425619	38/142 (27%)
		Arrestin_C	187..314	CDD:214976	31/134 (23%)
		PPxY motif 1. /evidence=ECO:0000305	346..349		1/2 (50%)
		PPxY motif 2. /evidence=ECO:0000305	391..394		2/2 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	393..414		6/23 (26%)