Protein Alignment CG18745 and aly2

DIOPT Version :10

• Sequence 1: NP_652648.1
• Gene: CG18745 / 59141
• FlyBaseID: FBgn0042102
• Length: 433
• Species: Drosophila melanogaster
• Sequence 2: NP_596223.1
• Gene: aly2 / 2540410
• PomBaseID: SPBC2D10.04
• Length: 658
• Species: Schizosaccharomyces pombe
• Alignment Length: 504
• Identity: 98/504 - (19%)
• Similarity: 163/504 - (32%)
• Gaps: 189/504 - (37%)

  Fly     5 CEIDFDNNPHGTYFGGEVLTGRVTLKLDKMKLVKAITLNITGYAETRWIERVTTNRRRRRRTFCG 69
            |:|:   ||       .:|.|.:.|::.|...::.|:|:.||.:.|.|.|.:...         |
pombe   168 CQIE---NP-------ALLRGALVLRVAKPANIRGISLSFTGRSRTEWPEGIPVK---------G 213

  Fly    70 REDY----IASKTF---------------------LVGSNL----SSQVSIEA------GIHTYN 99
            .:.|    |.|..:                     |||..|    |:..|:..      |.:|||
pombe   214 HDTYEDKVIISHNWKFYEPTMKDADAPQHGADVARLVGEQLPLPSSAAASLRGYSVFAPGEYTYN 278

  Fly   100 FVCLIPTECPSSFEGSHGRVRYMATVTLVRPWKFDQSYTRCFTVLKVMDLNFDSP--LLRVPAHS 162
            |...||...|.|.|...|.|||....|:.|           |...| .:||..:|  |:|.|:.:
pombe   279 FDLAIPNCFPESVEAKMGWVRYFLEATVER-----------FGTFK-SNLNGRTPVQLVRTPSPA 331

  Fly   163 ETSKTYCC-----WPCRSDPLALQLTVPQTGFVPGQNVPLSVLVTNDSHIPVEQLLISFVMLVTY 222
            ..|.:...     |   .:.|..:|.|....|..|:.||::........:.:.:|.||.|....|
pombe   332 SLSSSELINISRDW---DERLHYELQVSGKSFRLGEVVPITFRFLLLDKVRLYKLSISVVESSEY 393

  Fly   223 -------HSKPP---------SMPNTTSERLVVNTFKGDAVQRNCKKLFSYEIRVPATPPTCF-- 269
                   |...|         |..:..::.|.....:||.:.   ..:|::.:.:    |||.
pombe   394 WCRSRKFHRVDPKRRVLLAERSAKHQNTDNLFETPDEGDGLS---SAVFNFNVAL----PTCLVK 451

  Fly   270 ------------------NLCGIIQIAYQ--------------VEVEARVKGCH----------- 291
                              .|..::.::.:              :|...|:..|.
pombe   452 ERDRLTFDTTYKYIKVRHRLKALLVLSIENTENPEKRKYFEINIETPVRILSCRCVKDSTLLPPY 516

  Fly   292 -------NNEVVTIPLTIGSVPLAQHV-PIQPRGFVPQLNVNELAVEEVATAPNSSSPWSVDAS- 347
                   |..::..|..:.:.    || |.:...|..|   :.||    ::||::..|.:...|
pombe   517 ESSSQGDNQVLLPCPCRLATT----HVEPTEVTAFTTQ---SVLA----SSAPSAGRPAAAQISR 570

  Fly   348 -------------------------IPPPNYQEAVHMRSTAATRSDDLD 371
                                     .|||||.|...:.|:.:.:..:.|
pombe   571 PAQLFRIPSTNPPPFDGDVCPPACNTPPPNYDELFDVLSSISIQDCETD 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18745	NP_652648.1	Arrestin_N	5..150	CDD:425619	43/179 (24%)
		Arrestin_C	174..307	CDD:214976	28/200 (14%)
		TMEM52	<332..377	CDD:464418	12/66 (18%)
aly2	NP_596223.1	Arrestin_N	178..326	CDD:451447	42/168 (25%)
		Arrestin_C	345..506	CDD:214976	27/170 (16%)