DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18744 and CSR2

DIOPT Version :9

Sequence 1:	NP_652647.2	Gene:	CG18744 / 59140	FlyBaseID:	FBgn0042101	Length:	410	Species:	Drosophila melanogaster
Sequence 2:	NP_015355.1	Gene:	CSR2 / 856142	SGDID:	S000006234	Length:	1121	Species:	Saccharomyces cerevisiae

Alignment Length:	433	Identity:	75/433 - (17%)
Similarity:	129/433 - (29%)	Gaps:	153/433 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 TLSERALIKAICLEANGYASTAW---QQPQKHKNQKKNEQPVVVQSLDFDYRVDYFAKIDYFVGS 90
            :|::...:..|.:|........|   ..|.|:    .||:...:.|||:....|.|   :.|:..
Yeast   359 SLNKSTTLSDIKVELTSNVRVVWFNGLPPTKN----VNEECYNIGSLDWTLNADNF---NLFIPQ 416

  Fly    91 EAAQPQIMEAGTYNYGFHVKLPKNCPGNFEGGHGHIRYTLQVLIHSSADRPLEVLH---VRQLQI 152
            .|..|                                  |.::.:.|.:|.|:||.   :|:.:.
Yeast   417 GAKSP----------------------------------LDIVENHSNNRKLKVLQKLSMRKRRS 447

  Fly   153 FPQNSLSQETRSCEIQIYEQTPRLR----FWMKPLHLQLQIPRQGYSPGAGISVHLKLHNPEKLT 213
            |...::.:|.....:.....|.:|.    .:..|:.|..:||...|.|.|.:|..|:|
Yeast   448 FSNKAVLRENILNNLNASNSTNKLNAGVYVFTIPIVLASRIPESLYYPSARVSYSLRL------- 505

  Fly   214 LREAVYSLVQISTYVAHLKNKPKRLETKVERQTVLSSRHELHNLP--------------RGELQN 264
                          ...||::..:|.....|.:.:||..:|.:..              .||..|
Yeast   506 --------------ATKLKDEHTQLVASRPRSSSISSPQKLRSYSCSDSYEYSQIDDTIEGETYN 556

  Fly   265 FQHLHMLQVPQTAATLTVA---------------------GCA-------CLQLNYEVEVLVTTQ 301
            .......::...::.|..|                     |.|       .:.|.|.:. ||.|.
Yeast   557 NDKNSTGKIAFPSSWLKSAKGRLKRNNSNGRSDNNGASSSGLAMQHDSEDTINLQYPLN-LVRTP 620

  Fly   302 QEKRLIAARMPVIIGNVTPPCPGKLLMQE--------PIDGTAPEPTPPVETASTLIPNFSISTT 358
            .|..:..|..|:.|..|...|    |..|        |::|..|               .:|...
Yeast   621 PEISVTTANKPLYINKVWENC----LSYEISFAQKYVPLNGEIP---------------ITIKVA 666

  Fly   359 SLASNFREAEFMVATNLNKTNKHYLSGEQLDFRPRYVYYEMDQ 401
            .|..:.......|:..           |::.:|.:...|:.||
Yeast   667 PLVKSLSVKRIRVSCR-----------EKISYRSKDYQYDFDQ 698

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18744	NP_652647.2	Arrestin_N	5..141	CDD:304627	18/114 (16%)
CG18744	NP_652647.2	Arrestin_C	179..322	CDD:214976	34/184 (18%)
CSR2	NP_015355.1	Arrestin_C	638..>737	CDD:214976	14/91 (15%)
CSR2	NP_015355.1	Arrestin_C	<828..926	CDD:413500
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343376
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3780
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11188
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.930