Protein Alignment CG18744 and ROG3

DIOPT Version :10

• Sequence 1: NP_652647.2
• Gene: CG18744 / 59140
• FlyBaseID: FBgn0042101
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_116677.3
• Gene: ROG3 / 850578
• SGDID: S000001918
• Length: 733
• Species: Saccharomyces cerevisiae
• Alignment Length: 473
• Identity: 76/473 - (16%)
• Similarity: 158/473 - (33%)
• Gaps: 131/473 - (27%)

  Fly    22 VNGHVYLTLSERALIKAICLEANG--YASTAWQQPQKHKNQKKNEQPVVVQSLD---FDY----- 76
            ::|.:.|:::|...||:|.|...|  ......::||...:...:..|..::..:   ::|
Yeast    42 LSGCIVLSINEPMQIKSISLRLYGKIQIDVPLERPQDASSSSLSSSPPKIRKYNKVFYNYAWDNV 106

  Fly    77 -----------------------------RVDYFAKIDYFVGSEAAQPQIMEAGTYNYGFHVKLP 112
                                         |....:.:....||.:.....::.|.|::.|...||
Yeast   107 NLKEYLSGLRGQSGLAGSSSSSNILGTRQRAQSTSSLKSLKGSSSPSSCTLDKGNYDFPFSAILP 171

  Fly   113 KNCPGNFEG-GHGHIRYTLQVLIHSSAD-------RPLEVLHVRQLQIFPQNSLSQETRSCEIQI 169
            .:.|.:.|. .:..:.|:::.:|..|.:       :.:.||..    |.|          ..:::
Yeast   172 GSLPESVESLPNCFVTYSMESVIERSKNYSDLICRKNIRVLRT----ISP----------AAVEL 222

  Fly   170 YEQTPRLRFWMKPLHLQLQIPRQGYSPGAGISVHLKLHNPEKLTLREAVYSLVQISTYVAHLKNK 234
            .|.......|...:...:.:|.:..:.|:...:::.: .|....|:.....:|....|.......
Yeast   223 SETVCVDNSWPDKVDYSISVPNKAVAIGSATPINISI-VPLSKGLKLGSIKVVLFENYQYCDPFP 286

  Fly   235 PKRLETKVERQTVLSSRHELHNLPRGELQN---------FQHLH----------MLQVPQTAATL 280
            |...|   .||....:..:..|...||...         ||..|          :||:|.:.:.
Yeast   287 PVISE---NRQVTELNLEDPLNESSGEFNGNGCFVNNPFFQPDHSFQDKWEIDTILQIPNSLSN- 347

  Fly   281 TVAGC---ACLQLNYEVE---VLVTTQQEKRLIAARMPVIIGNVTPPCPGKLLMQEPIDGTAPEP 339
            .|..|   :.:::.::::   :|:.....|..:.|.:|:            .|...|....:.:|
Yeast   348 CVQDCDVRSNIKVRHKLKFFIILINPDGHKSELRASLPI------------QLFISPFVALSIKP 400

  Fly   340 TPPVETASTLIPNFSISTTSL----ASNFREAEFMVATNLNKTNKHYLSGEQLDFR--------- 391
            .    ::|.|...|  |||:.    :|...|.|::.:.:.:.|....|:    |.|
Yeast   401 L----SSSNLYSLF--STTNQKDENSSQEEEEEYLFSRSASVTGLELLA----DMRSGGSVPTIS 455

  Fly   392 -----PRYVYYEMDQTQS 404
                 |.|..:..|:..|
Yeast   456 DLMTPPNYEMHVYDRLYS 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18744	NP_652647.2	Arrestin_N	5..141	CDD:451447	25/165 (15%)
		Arrestin_C	179..318	CDD:460676	26/163 (16%)
ROG3	NP_116677.3	Arrestin_N	<156..215	CDD:451447	12/62 (19%)
		Arrestin_C	232..393	CDD:214976	27/177 (15%)