Protein Alignment CG18744 and ARRDC5

DIOPT Version :9

• Sequence 1: NP_652647.2
• Gene: CG18744 / 59140
• FlyBaseID: FBgn0042101
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_001354118.1
• Gene: ARRDC5 / 645432
• HGNCID: 31407
• Length: 350
• Species: Homo sapiens
• Alignment Length: 378
• Identity: 73/378 - (19%)
• Similarity: 129/378 - (34%)
• Gaps: 88/378 - (23%)

  Fly     6 EIQLDNPRGVYRAGDTVNGHVYLTLSERALIKAICLEANGYASTAWQQPQKHKNQKKNEQPVVVQ 70
            |:.|...| :|.||.::.|.|.|||:...:...:.:|..|.....|.:.             ...
Human     8 ELVLPEDR-IYLAGSSIKGQVILTLNSTLVDPIVKVELVGRGYVEWSEE-------------AGA 58

  Fly    71 SLDFDYRV------DYFAKIDYFVGSEAAQPQIMEAG--------------TYNYGFHVKLPK-- 113
            |.|:...|      ||..|...|...|.|...:.:||              |:....|:.|..
Human    59 SCDYSRNVICNNKADYVHKTKTFPVEEMASRSVTQAGVQWHDLGSLQPPSRTFKLSSHLSLLSTW 123

  Fly   114 --NCPGNFEGGHGHIRYTLQVLIHSSADRPLEVLHVRQLQIFPQNSLSQETRSCEIQIYEQTPRL 176
              ..|..|....||:.|.:|.   |...|. .:|..:::.:..|.:.:         .:::||
Human   124 NYRLPSTFTSKFGHVFYFVQA---SCMGRE-HILAKKRMYLLVQGTST---------FHKETP-- 173

  Fly   177 RFWMKPLH------------------LQLQIPRQGYSPGAGISVHLKLHNPEKLTLREAVYSLVQ 223
              :..||.                  ||:|:.|..::||..:....:::|.....::..|::|
Human   174 --FQNPLFVEAEEKVSYNCCRQGTVCLQIQMERNTFTPGEKVVFTTEINNQTSKCIKTVVFAL-- 234

  Fly   224 ISTYVAHLKNKPKRLETKVERQTVLSSRHELHNLPRGELQNFQHLHMLQVPQTAATLTVAGCA-- 286
                .||::.  :......||::.|.|...|.......:..|....::........|:|:...
Human   235 ----YAHIQY--EGFTPSAERRSRLDSSELLRQEANTPVTRFNTTKVVSTFNLPLLLSVSSSTQD 293

  Fly   287 --CLQLNYEVEVLVTTQQEKRLIAARMPVIIGNVTPPCPGKLLMQEPIDGTAP 337
              .:...||:...|........:.|::|:||   |.......:.|...||..|
Human   294 GEIMHTRYELVTTVHLPWSLTSLKAKVPIII---TSASVDSAICQLSEDGVLP 343

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18744	NP_652647.2	Arrestin_N	5..141	CDD:304627	35/158 (22%)
		Arrestin_C	179..322	CDD:214976	29/164 (18%)
ARRDC5	NP_001354118.1	Arrestin_N	13..146	CDD:328947	32/149 (21%)
		Arrestin_C	192..326	CDD:308405	26/144 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145959
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D817924at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11188
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.950