Protein Alignment CG18744 and Leash

DIOPT Version :10

• Sequence 1: NP_652647.2
• Gene: CG18744 / 59140
• FlyBaseID: FBgn0042101
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_650037.2
• Gene: Leash / 41320
• FlyBaseID: FBgn0037856
• Length: 520
• Species: Drosophila melanogaster
• Alignment Length: 437
• Identity: 97/437 - (22%)
• Similarity: 171/437 - (39%)
• Gaps: 91/437 - (20%)

  Fly     2 SHRCEIQLDNPRGVYRAGDTVNGHVYLTLSERALIKAICLEANGYASTAWQQPQKHKNQKKNEQP 66
            |.|..|.||:...||.|||.:.|.:::.:::|..|:||.::..|.....|.:..: ||...||..
  Fly     3 SERLRITLDSADRVYFAGDIIRGEIWMNVNKRTKIRAIKVQVTGKGKCKWMEILR-KNSNNNEYS 66

  Fly    67 VVVQSLDFDYRVDYFAKIDYFVGSEAAQPQI------MEAGTYNYGFHVKLPKNCPGNFEGGHGH 125
               :||       ::...:.:..||...|..      :.||.:.:.|.|.|.:..|.:|:|.:|.
  Fly    67 ---RSL-------FYTSKEVYEHSETPLPDFEPRGLELSAGEHTFIFEVALGRQLPSSFKGSYGA 121

  Fly   126 IRYTLQVLIHSSADRP--LEVLHVRQLQIFPQNSLSQETRSCEIQIYEQTPRL--RFWMKPLHLQ 186
            |:|.::|||    .||  .:..|.....:.....|....||....:.:|..:.  .|..:|:.|.
  Fly   122 IKYKMRVLI----QRPWTFDERHTIPFTVVKNMPLQPMQRSIPSSLEKQVTKTISLFGTRPITLL 182

  Fly   187 LQIPRQGYSPGAGISVHLKLHNPEKLTLREAVYSLVQISTYVAHLKNKPKRLE-----TK----V 242
            ..:|......|..:.:...:.|.....:.:..::::|..||.:|:..:.:::|     ||    |
  Fly   183 ALLPEDFAVRGEPLRICATVINNSTTAVEKLRFTVLQYVTYYSHVPLRVQKVECIAVATKETGSV 247

  Fly   243 ERQTVLSSRHELHNLPRGELQNFQHLHMLQVPQTAATLTVAGCACLQLNYEVEVLVTTQQEKRLI 307
            :::|..|..||| .||.|.....:        |.:..:|:.        ||:.|....:...:.:
  Fly   248 QKKTERSFAHEL-LLPDGAQPTDE--------QMSGVITIV--------YELRVEAVLRGFFKNL 295

  Fly   308 AARMPVII---------GNVTPPCPGKLLMQEPIDGTAPEPTPPV------ETASTLIPNF--SI 355
            ...:|..:         .::.||.|.:     |.||   .|.|.:      |.|..:.|:.  ||
  Fly   296 ILNLPFKVYSQDPSNRQSSLRPPPPPR-----PNDG---PPGPELGSGNLFEPALPVYPSLDSSI 352

  Fly   356 STTSLASNFREAEFM---------------VATNLNKTNKHYLSGEQ 387
            .:.|.:|.|.|...:               |.......:..|.||.|
  Fly   353 GSPSHSSQFSECSSINSITSDSSAATLSPAVGAGTGGMDMSYTSGSQ 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18744	NP_652647.2	Arrestin_N	5..141	CDD:451447	38/141 (27%)
		Arrestin_C	179..318	CDD:460676	27/156 (17%)
Leash	NP_650037.2	Arrestin_N	6..152	CDD:451447	41/160 (26%)
		Arrestin_C	191..308	CDD:214976	24/133 (18%)