Protein Alignment CG18744 and TXNIP

DIOPT Version :9

• Sequence 1: NP_652647.2
• Gene: CG18744 / 59140
• FlyBaseID: FBgn0042101
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: XP_016855574.1
• Gene: TXNIP / 10628
• HGNCID: 16952
• Length: 395
• Species: Homo sapiens
• Alignment Length: 405
• Identity: 88/405 - (21%)
• Similarity: 151/405 - (37%)
• Gaps: 131/405 - (32%)

  Fly     6 EIQLDNPRGVYRAGDTVNGHVYLTLSERALIKAICLEANGYASTAWQQPQKHKNQKKNEQPVVVQ 70
            |:..::|..||.:|:.|.|.|.:.:.|...:||:.:.|.|.|...|.|..:...|..
Human    11 EVVFNDPEKVYGSGEKVAGRVIVEVCEVTRVKAVRILACGVAKVLWMQGSQQCKQTS-------- 67

  Fly    71 SLDFDYRVDYFAKIDYFVGSEAAQPQ------IMEAGT-YNYGFHVKLPKNCPG-NFEGGHGHIR 127
                    :|....|..:..:  ||.      ||..|. |.|.|..:||:...| :|:|.:|.:.
Human    68 --------EYLRYEDTLLLED--QPTGENEMVIMRPGNKYEYKFGFELPQGPLGTSFKGKYGCVD 122

  Fly   128 YTLQVLIHSSADRPLEVLHVRQLQIFPQNSLSQETRSCEIQIYE----QTPRLRFWMKP------ 182
            |.::..:    |||              :..:|||:. ..::.:    .||.|   |.|
Human   123 YWVKAFL----DRP--------------SQPTQETKK-NFEVVDLVDVNTPDL---MAPVSAKKE 165

  Fly   183 ------------LHLQLQIPRQGYSPGAGISVHLKLHNP-EKLTLREAVYSLVQISTYVAHLKNK 234
                        :.:..:|.|:|:..|..||:|....|. .::.:.:|  ::|...||:|:
Human   166 KKVSCMFIPDGRVSVSARIDRKGFCEGDEISIHADFENTCSRIVVPKA--AIVARHTYLAN---- 224

  Fly   235 PKRLETKVERQTVLSSRHELHNLP------RGELQNFQHLHMLQVPQTAATLTVAGCACLQLNYE 293
               .:|||..|. |||....|.:.      ||:....|.:..          ::.||..|::.|.
Human   225 ---GQTKVLTQK-LSSVRGNHIISGTCASWRGKSLRVQKIRP----------SILGCNILRVEYS 275

  Fly   294 VEVLVTTQQEKRLIAARMPVIIG-------------------------NV-----TPPCPGKLLM 328
            :.:.|:....|::| ..:|::||                         |:     .|||...::
Human   276 LLIYVSVPGSKKVI-LDLPLVIGSRSGLSSRTSSMASRTSSEMSWVDLNIPDTPEAPPCYMDVI- 338

  Fly   329 QEPIDGTAPEPTPPV 343
              |.|.....||.|:
Human   339 --PEDHRLESPTTPL 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18744	NP_652647.2	Arrestin_N	5..141	CDD:304627	35/142 (25%)
		Arrestin_C	179..322	CDD:214976	38/197 (19%)
TXNIP	XP_016855574.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3780
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D311636at33208
OrthoFinder	1	1.000	-	-		FOG0000089
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X122
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.820