DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and egflam

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	XP_009299464.1	Gene:	egflam / 799405	-ID:	-	Length:	1056	Species:	Danio rerio

Alignment Length:	235	Identity:	48/235 - (20%)
Similarity:	79/235 - (33%)	Gaps:	79/235 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 ATPSLRSASDPEKILNNLAQLRQSSFLDWIQSILGP-----EVPAEWS-SPAKREC--------A 70
            |||.:|:|:.|..:.::     ..|...|    .|.     :||.|.: .||...|        :
Zfish   352 ATPIVRTATPPPAVPSS-----SPSMTPW----KGERARVYDVPCEETVCPADSFCINDYDTGGS 407

  Fly    71 ECSCGNINTRHRIVGGQETEVHEYPWMIMLMWFGNFYCGASLVNDQYALTAAHCVN-----GFYH 130
            .|.|.        :|.|                |:| |...|.           :|     |:.|
Zfish   408 RCHCN--------LGRQ----------------GDF-CSEGLT-----------INFPKFYGYSH 436

  Fly   131 RLITVRLLEHNRQDSHVKIVDRRVSR--VLIH---PKYSTRNFDSDIALIRFNEPVRLGIDMHPV 190
              :|...|:::.|...:.:..:..:.  :|::   .::...:|.| :||||.....|........
Zfish   437 --MTFEPLKNSYQSFQISLEFKAEAEDGLLLYCGENEHGRGDFTS-LALIRGKLHYRFNCGTGAA 498

  Fly   191 CMPTPSENYAGQTAVVT-------GWGALSEGGPISDTLQ 223
            .:.:.|....||...||       ||..|....|:|...|
Zfish   499 QIISDSSIVIGQWHTVTIFRDGMNGWLRLDNDTPVSSRSQ 538

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	31/159 (19%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	31/158 (20%)
egflam	XP_009299464.1	FN3	35..142	CDD:238020
		FN3	151..237	CDD:238020
		LamG	431..581	CDD:238058	24/111 (22%)
		EGF_CA	600..642	CDD:238011
		LamG	658..805	CDD:238058
		EGF	828..858	CDD:278437
		Laminin_G_2	908..1033	CDD:280389
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910