DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and tmprss7

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	XP_002666699.2	Gene:	tmprss7 / 798480	ZFINID:	ZDB-GENE-130530-883	Length:	840	Species:	Danio rerio

Alignment Length:	268	Identity:	101/268 - (37%)
Similarity:	151/268 - (56%)	Gaps:	33/268 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 CSCG----------NINTRHRIVGGQETEVHEYPWMIMLMWFGNFYCGASLVNDQYALTAAHCVN 126
            |:||          ..:.:.|||||......|:||.:.:.:.|..|||||:::|.:.::||||.:
Zfish   581 CACGKPTHVKRVLDGTSPQQRIVGGVNAVEGEWPWQVSMHFSGQLYCGASVLSDVWLISAAHCYS 645

  Fly   127 GFYHRLITVRLLEHNRQDSHVKIVDR-------RVSRVLIHPKYSTRNFDSDIALIRFNEPVRLG 184
                   ..||.:.....:|:.::::       .:.|:::|..|:.||||.||||::..:....|
Zfish   646 -------KERLADPRMWMAHLGMLNQGSAKHVAEIRRIVVHEYYNARNFDYDIALLQLKKVWPSG 703

  Fly   185 IDMH--PVCMPTPSENYA-GQTAVVTGWGALSEGGPISDT-LQEVEVPILSQEECRNSNYGESKI 245
            ::.:  |||:|.||:.:. |....|||||..||...:..| ||:.||.:|||.||:.| ||  .:
Zfish   704 LEQYIQPVCLPAPSQTFTEGHRCWVTGWGYRSEQDKVLPTVLQKAEVNVLSQSECKRS-YG--PV 765

  Fly   246 TDNMICAGYVEQGGKDSCQGDSGGPMHVLG-SGDAYQLAGIVSWGEGCAKPNAPGVYTRVGSFND 309
            :..|:||| |..|.:|:|:||||||:.... :|..:.|.||||||.||.:|..|||||||..|.|
Zfish   766 SPRMLCAG-VPSGEQDACRGDSGGPLSCQAQTGSRWFLTGIVSWGSGCGRPYLPGVYTRVAKFID 829

  Fly   310 WIAENTRD 317
            ||..:..|
Zfish   830 WIQRHIHD 837

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	95/240 (40%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	96/242 (40%)
tmprss7	XP_002666699.2	SEA	99..203	CDD:307516
		CUB	<260..344	CDD:238001
		CUB	367..465	CDD:294042
		LDLa	472..506	CDD:238060
		LDLa	546..581	CDD:238060	101/268 (38%)
		Tryp_SPc	601..831	CDD:214473	95/240 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910