DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and f7

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	NP_001072819.1	Gene:	f7 / 780280	XenbaseID:	XB-GENE-5787186	Length:	452	Species:	Xenopus tropicalis

Alignment Length:	297	Identity:	107/297 - (36%)
Similarity:	150/297 - (50%)	Gaps:	43/297 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 SSPAKRECA------------ECS------CG------NINTRHRIVGGQETEVHEYPWMIMLMW 102
            :|...|:|:            .|.      ||      |:|.|.|||||......|.||..:||:
Frog   167 NSSTSRQCSCAEGYKLGADGLSCEPTVNYPCGKIPVLKNVNKRARIVGGDMCPKGECPWQALLMY 231

  Fly   103 FGNFYCGASLVNDQYALTAAHCVNGFYHRLITVRLLEHNRQDSHVKIVDRRVSRVLIHPKY--ST 165
            ...|.||.:|:...:.:|||||:.......:||.|.||..........:.:||::::|..|  |.
Frog   232 NEIFICGGTLIAPNWVITAAHCLKPLPENKLTVVLGEHRIGTPEGTEQESKVSKIIMHEHYYGSK 296

  Fly   166 RNFDSDIALIRFNEPVRLGIDMHPVCMPTPSENYAGQT------AVVTGWGALSEGGPISDTLQE 224
            .|.|:||||::...||.....:.|:|:  |.:.:|.|.      :.|:|||.|.|.|...:.||.
Frog   297 TNNDNDIALLKLTTPVNYTDYVVPLCL--PEKQFAVQELLSIRYSTVSGWGRLLESGATPELLQR 359

  Fly   225 VEVPILSQEECRNSNYGESKITDNMICAGYVEQGGKDSCQGDSGGPMHVLGSGDAYQLAGIVSWG 289
            |::|.:..::|....  :..|:.||.||||.: |.||||:|||||| |.....:.:.|.||||||
Frog   360 VQLPRVKTQDCIRQT--QMNISQNMFCAGYTD-GSKDSCKGDSGGP-HATQYKNTHFLTGIVSWG 420

  Fly   290 EGCAKPNAPGVYTRVGSFNDWIAENTRDACSCAQPEA 326
            .||||....||||||..:.:||.||..:     ||||
Frog   421 LGCAKKEKYGVYTRVSRYTEWIKENMDE-----QPEA 452

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	90/236 (38%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	91/238 (38%)
f7	NP_001072819.1	Gla	67..107	CDD:366184
		EGF_CA	108..144	CDD:238011
		FXa_inhibition	153..189	CDD:373209	3/21 (14%)
		Tryp_SPc	212..445	CDD:238113	91/238 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910