DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and st14b

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	XP_005161261.1	Gene:	st14b / 777629	ZFINID:	ZDB-GENE-061103-613	Length:	864	Species:	Danio rerio

Alignment Length:	276	Identity:	112/276 - (40%)
Similarity:	162/276 - (58%)	Gaps:	16/276 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 SILGPEVPAEWSSPAKRECAECSCG-NINTRHRIVGGQETEVHEYPWMIML-MWFGNFYCGASLV 113
            |.|.|....|.......:.|||.|| ..:...|||||::::..|:||.:.| |......||||::
Zfish   592 SKLNPMCDGETDCVDGSDEAECKCGKKPHKSSRIVGGKDSDEGEWPWQVSLHMKTQGHVCGASVI 656

  Fly   114 NDQYALTAAHCV---NGFYHRLI---TVRLLEHNRQDSHVKIVDRRVSRVLIHPKYSTRNFDSDI 172
            ::.:.:||||||   :.|.:...   .|.|..||:.::. |...|.|.|::.||:|...::|:||
Zfish   657 SNSWLVTAAHCVQDNDQFRYSQADQWEVYLGLHNQGETS-KSTQRSVLRIIPHPQYDHSSYDNDI 720

  Fly   173 ALIRFNEPVRLGIDMHPVCMPTPSENY-AGQTAVVTGWGALSEGG-PISDTLQEVEVPILSQEEC 235
            ||:..:.||.|..::.|:|:|.|:..: ||::..:||||.|.||. .:...||:.||.|::...|
Zfish   721 ALMELDSPVTLNQNIWPICLPDPTHYFPAGKSVWITGWGKLREGSDAVPSVLQKAEVRIINSTVC 785

  Fly   236 RNSNYGESKITDNMICAGYVEQGGKDSCQGDSGGPM-HVLGSGDAYQLAGIVSWGEGCAKPNAPG 299
              |...:..||.:||||| |..||.|:||||||||| .:.|:|..: |||:||||:||.:.|.||
Zfish   786 --SKLMDDGITPHMICAG-VLSGGVDACQGDSGGPMSSIEGNGRMF-LAGVVSWGDGCGRRNRPG 846

  Fly   300 VYTRVGSFNDWIAENT 315
            |||||..:..||.|.|
Zfish   847 VYTRVTDYRSWIREIT 862

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	99/238 (42%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	100/240 (42%)
st14b	XP_005161261.1	SEA	92..180	CDD:279699
		CUB	233..342	CDD:238001
		CUB	351..457	CDD:238001
		LDLa	465..497	CDD:238060
		LDLa	499..533	CDD:238060
		LDLa	536..570	CDD:238060
		LDLa	578..613	CDD:238060	5/20 (25%)
		Tryp_SPc	624..858	CDD:214473	99/238 (42%)
		Tryp_SPc	625..861	CDD:238113	100/240 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm6416
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.810