DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and Prss36

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	XP_017167884.1	Gene:	Prss36 / 77613	MGIID:	1924863	Length:	863	Species:	Mus musculus

Alignment Length:	360	Identity:	119/360 - (33%)
Similarity:	168/360 - (46%)	Gaps:	59/360 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 FLDWIQSILGPEVPAEWS----SPAKRECAECSCGNINTRHRIVGGQETEVHEYPWMIMLMWFGN 105
            ||..:..::.|..|..:.    ||.:.|..:..||......|||||.:.....:||.:.|...|.
Mouse     6 FLPVVIMVVSPIPPGAFQDSVVSPTQGEFEDLDCGRPEPSSRIVGGSDAHPGTWPWQVSLHQGGG 70

  Fly   106 FYCGASLVNDQYALTAAHC--VNGFYHRL--ITVRLLEHNR----QDSHVKIVDRRVSRVLIHPK 162
            ..||.||:...:.|:||||  .||.....  ::|.|..|::    :.:|:    |.|:.:||...
Mouse    71 HICGGSLIAPSWVLSAAHCFVTNGTLEPADELSVLLGVHSQDGPLEGAHM----RSVATILIPDN 131

  Fly   163 YSTRNFDSDIALIRFNEPVRLGIDMHPVCMPTPSENYAGQTAV-VTGWGALSEGG--PISDTLQE 224
            |||....:|:||:|...|.:||..:.|||:|..|..:|..||. .||||.:.|..  |:...|||
Mouse   132 YSTVELGADLALLRLASPAKLGPSVRPVCLPRASHLFAHGTACWATGWGDVQEAVPLPLPWVLQE 196

  Fly   225 VEVPILSQE--ECRNSNYGESKIT----DNMICAGYVEQGGKDSCQGDSGGPMHVLGSGDAYQLA 283
            ||:.:|.:.  :|..|..|...:|    ..|:|||| ..|.:|:||||||||: |...|..:.||
Mouse   197 VELRLLGEAACQCLYSRPGPFNLTFQLLPGMLCAGY-PAGRRDTCQGDSGGPL-VCEDGGRWFLA 259

  Fly   284 GIVSWGEGCAKPNAPGVYTRVGSFNDWIAENT------------------------RDACSCAQP 324
            ||.|:|.||.:.|.|||:|.|..:..||.|:.                        .:.|:.|||
Mouse   260 GITSFGFGCGRRNRPGVFTAVAPYESWIREHVMGSEPGPVFPSQLQKPQSGPWEPREENCTFAQP 324

  Fly   325 EAAGEPAS---PME--TTEQGDQENTTANGAAEAD 354
            |....|..   |.|  .|..|   :|...||..:|
Mouse   325 ECGKAPRPGTWPWEAQVTVPG---STPCYGALVSD 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	93/245 (38%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	94/247 (38%)
Prss36	XP_017167884.1	Tryp_SPc	48..290	CDD:238113	94/247 (38%)
		Tryp_SPc	331..532	CDD:389826	8/29 (28%)
		Tryp_SPc	607..789	CDD:389826
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810