Protein Alignment CG18735 and TPSAB1

DIOPT Version :10

• Sequence 1: NP_652645.1
• Gene: CG18735 / 59137
• FlyBaseID: FBgn0042098
• Length: 364
• Species: Drosophila melanogaster
• Sequence 2: NP_003285.2
• Gene: TPSAB1 / 7177
• HGNCID: 12019
• Length: 275
• Species: Homo sapiens
• Alignment Length: 263
• Identity: 103/263 - (39%)
• Similarity: 147/263 - (55%)
• Gaps: 24/263 - (9%)

  Fly    65 AKRECAECSCGNINTRHRIVGGQETEVHEYPWMIMLMWFGNF---YCGASLVNDQYALTAAHCVN 126
            |.|..|..:.|....|..||||||....::||.:.|...|.:   :||.||::.|:.|||||||.
Human    13 ASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVG 77

  Fly   127 GFYHRLITVRLLEHNRQDSHVKIVDR--RVSRVLIHPKYSTRNFDSDIALIRFNEPVRLGIDMHP 189
            .....|..:|:   ..::.|:...|:  .|||:::||::.|....:||||:...|||.:...:|.
Human    78 PDVKDLAALRV---QLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHT 139

  Fly   190 VCMPTPSENY-AGQTAVVTGWGAL--SEGGPISDTLQEVEVPILSQEECRNSNY------GESK- 244
            |.:|..||.: .|....|||||.:  .|..|....|::|:|||:....| ::.|      |:..
Human   140 VTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHIC-DAKYHLGAYTGDDVR 203

  Fly   245 -ITDNMICAGYVEQGGKDSCQGDSGGPMHVLGSGDAYQLAGIVSWGEGCAKPNAPGVYTRVGSFN 308
             :.|:|:|||...   :||||||||||:....:|...| ||:||||||||:||.||:||||..:.
Human   204 IVRDDMLCAGNTR---RDSCQGDSGGPLVCKVNGTWLQ-AGVVSWGEGCAQPNRPGIYTRVTYYL 264

  Fly   309 DWI 311
            |||
Human   265 DWI 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	98/245 (40%)
TPSAB1	NP_003285.2	Tryp_SPc	31..268	CDD:238113	98/245 (40%)