DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and st14a

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	NP_001035441.2	Gene:	st14a / 678603	ZFINID:	ZDB-GENE-030131-6496	Length:	834	Species:	Danio rerio

Alignment Length:	260	Identity:	102/260 - (39%)
Similarity:	146/260 - (56%)	Gaps:	24/260 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 AECSCG-NINTRHRIVGGQETEVHEYPWMIMLMWFGNF--YCGASLVNDQYALTAAHCVN----- 126
            :.|:|| ....:.||||||:....|:||.:.| ...|.  .||.|::|:::.:||||||.
Zfish   583 SNCNCGTKAYKKSRIVGGQDAFEGEFPWQVSL-HIKNIAHVCGGSIINERWIVTAAHCVQDDVKI 646

  Fly   127 -----GFYHRLITVRLLEHNRQDSHVKIVDRRVSRVLIHPKYSTRNFDSDIALIRFNEPVRLGID 186
                 |.:.    |.|..|:::|. :....|.:.:|:.||.|:...:|:||||:....||.....
Zfish   647 KYSQPGTWE----VFLGLHSQKDK-LTATKRLLKQVIPHPYYNAYTYDNDIALMEMESPVTFSDT 706

  Fly   187 MHPVCMPTPSENY-AGQTAVVTGWGALSEGGPISDTLQEVEVPILSQEECRNSNYGESKITDNMI 250
            :.|||:||.::.: ||.:..::||||..|||..:..||:.||.|::...|.....|:  ||..|.
Zfish   707 IRPVCLPTATDTFPAGTSVFISGWGATREGGSGATVLQKAEVRIINSTVCNQLMGGQ--ITSRMT 769

  Fly   251 CAGYVEQGGKDSCQGDSGGPMHVLGSGDAYQLAGIVSWGEGCAKPNAPGVYTRVGSFNDWIAENT 315
            ||| |..||.|:||||||||:. ..||....|||:||||:|||:.|.||:|:.|..|..||.|.|
Zfish   770 CAG-VLSGGVDACQGDSGGPLS-FPSGKRMFLAGVVSWGDGCARRNKPGIYSNVPKFRAWIKEKT 832

Fly 316 315
Zfish 833 832

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	95/241 (39%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	96/243 (40%)
st14a	NP_001035441.2	SEA	77..168	CDD:279699
		CUB	219..322	CDD:238001
		CUB	329..431	CDD:238001
		LDLa	443..472	CDD:238060
		LDLa	474..508	CDD:238060
		LDLa	510..544	CDD:238060
		LDLa	550..585	CDD:238060	0/1 (0%)
		Tryp_SPc	596..828	CDD:214473	95/241 (39%)
		Tryp_SPc	597..831	CDD:238113	96/243 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810