Protein Alignment CG18735 and PRSS22

DIOPT Version :10

• Sequence 1: NP_652645.1
• Gene: CG18735 / 59137
• FlyBaseID: FBgn0042098
• Length: 364
• Species: Drosophila melanogaster
• Sequence 2: XP_054169579.1
• Gene: PRSS22 / 64063
• HGNCID: 14368
• Length: 425
• Species: Homo sapiens
• Alignment Length: 324
• Identity: 105/324 - (32%)
• Similarity: 167/324 - (51%)
• Gaps: 41/324 - (12%)

  Fly    54 GPEV------PAEW----SSP-----AKRECAECSCGNINTRHRIVGGQETEVHEYPWMIMLMWF 103
            ||.|      |..|    |||     |.|.....:||.....:|:|||:::...|:||::.:...
Human   114 GPGVERLESLPGHWRARGSSPPAILNAARIPVPPACGKPQQLNRVVGGEDSTDSEWPWIVSIQKN 178

  Fly   104 GNFYCGASLVNDQYALTAAHC----VNGFYHRLITVRLLEHNRQDSHVKIVDRRVSRVLIHPKYS 164
            |..:|..||:..::.:|||||    :|..|...:.:...:.....|..:.|.  |:.|..||.||
Human   179 GTHHCAGSLLTSRWVITAAHCFKDNLNKPYLFSVLLGAWQLGNPGSRSQKVG--VAWVEPHPVYS 241

  Fly   165 TR-NFDSDIALIRFNEPVRLGIDMHPVCMPTPSENYAGQT-AVVTGWGALSEGGPI--SDTLQEV 225
            .: ...:||||:|....::....:.|:|:|..|.:....| ..::|||::.:|.|:  ..|||::
Human   242 WKEGACADIALVRLERSIQFSERVLPICLPDASIHLPPNTHCWISGWGSIQDGVPLPHPQTLQKL 306

  Fly   226 EVPILSQEECRNSNY---GESKITDNMICAGYVEQGGKDSCQGDSGGPMHVLGSGDAYQLAGIVS 287
            :|||:..|.|.:..:   |:..||::|:||||:| |.:|:|.||||||:.....| |:.||||:|
Human   307 KVPIIDSEVCSHLYWRGAGQGPITEDMLCAGYLE-GERDACLGDSGGPLMCQVDG-AWLLAGIIS 369

  Fly   288 WGEGCAKPNAPGVYTRVGSFNDWIAENTRDACSCAQPEAAGEPASPMETTEQGDQENTTANGAA 351
            ||||||:.|.||||..:.:...|:.:..:......:.:..|...:|    .||       :|||
Human   370 WGEGCAERNRPGVYISLSAHRSWVEKIVQGVQLRGRAQGGGALRAP----SQG-------SGAA 422

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	85/241 (35%)
PRSS22	XP_054169579.1	Tryp_SPc	158..396	CDD:238113	85/241 (35%)