DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and c1s

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	XP_002941253.2	Gene:	c1s / 613055	XenbaseID:	XB-GENE-995410	Length:	691	Species:	Xenopus tropicalis

Alignment Length:	290	Identity:	93/290 - (32%)
Similarity:	143/290 - (49%)	Gaps:	42/290 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 SSFLDWIQSILGPEVPAEWSSPAKRECAECSCGNINTRHRIVGGQETEVHEYPWMIML--MWFGN 105
            ||:..|:.|....|:|.  .:|.      |.....:...||.||...:..::||||..  :..|
Frog   405 SSYGYWVNSRGNKELPI--CTPV------CGVHQSDKSGRIFGGTRAKPGQFPWMIQFTDIELG- 460

  Fly   106 FYCGASLVNDQYALTAAHCVNGFYHRLI---TVRLLEHNRQDSHVKIVDRRVSRVLIHPKYSTR- 166
               |.||::|::.|||||.||......:   .::...:....|..|.:  :..:::|||.|...
Frog   461 ---GGSLISDRWVLTAAHVVNKKIFPTMFGGVMKFFPNTNLQSQEKRL--QAKKIIIHPLYQDNE 520

  Fly   167 ------NFDSDIALIRFNEPVRLGIDMHPVCMP----TPSENYAGQTAVVTGWGALSEGGPISDT 221
                  |||:||||::..:.|:||..:.|:|:|    .|..|   :.|.:.|||. :|....:..
Frog   521 DTEGQSNFDNDIALVQLTKKVKLGSCISPICLPRRGLAPVVN---EVATIAGWGK-TEKRESAVN 581

  Fly   222 LQEVEVPILSQEECRNSNYGESKITDNMICAGYVEQGGKDSCQGDSGGPMHVLGSGDAYQ--LAG 284
            ||...:.:.|.::|:.:..|:...|.||:|||  ...|||||.||||||:......|:.:  :||
Frog   582 LQFASISLSSMDKCKKATGGKGYFTPNMLCAG--SDVGKDSCNGDSGGPLMFTDPQDSSKMYMAG 644

  Fly   285 IVSWG-EGCAKPNAPGVYTRVGSFNDWIAE 313
            ||||| ..|   ...|:||:|.::.|||.|
Frog   645 IVSWGPRDC---GTYGLYTKVDNYLDWIEE 671

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	82/247 (33%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	84/250 (34%)
c1s	XP_002941253.2	CUB	21..131	CDD:238001
		FXa_inhibition	145..173	CDD:405372
		CUB	177..288	CDD:238001
		PHA02927	301..>436	CDD:222943	8/38 (21%)
		Tryp_SPc	436..669	CDD:214473	82/247 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910