DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and Prss21

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	NP_065233.2	Gene:	Prss21 / 57256	MGIID:	1916698	Length:	324	Species:	Mus musculus

Alignment Length:	320	Identity:	111/320 - (34%)
Similarity:	163/320 - (50%)	Gaps:	53/320 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LLLILATALGDLACATPSLRSASDPEKILNNLAQLRQSSFLDWIQSILGPEVPAEWSSPAKRECA 70
            ||:::|||    |.|..|.....||||     .:|::...|.      ||
Mouse    11 LLVVVATA----AMALQSTYLQVDPEK-----PELQEPDLLS------GP--------------- 45

  Fly    71 ECSCGNINTRHRIVGGQETEVHEYPWMIMLMWFGNFYCGASLVNDQYALTAAHCV---NGFYHRL 132
               ||:.....|||||.:.|:..:||...|..:||..|||:|:|.::.||||||.   |..:.
Mouse    46 ---CGHRTIPSRIVGGDDAELGRWPWQGSLRVWGNHLCGATLLNRRWVLTAAHCFQKDNDPFD-- 105

  Fly   133 ITVRLLEHNRQDS--HVKIVDRR--VSRVLIHPKYSTRNFDSDIALIRFNEPVRLGIDMHPVCMP 193
            .||:..|...:.|  :::....|  :..:.:.|||| ..:.:||||::.:.||.....:.|:|:.
Mouse   106 WTVQFGELTSRPSLWNLQAYSNRYQIEDIFLSPKYS-EQYPNDIALLKLSSPVTYNNFIQPICLL 169

  Fly   194 TPSENYAGQT-AVVTGWGALSEGG--PISDTLQEVEVPILSQEECRNSNYGE----SKITDNMIC 251
            ..:..:..:| ..||||||:.|..  |..:|||||:|.|::...| |..|.:    :.|..:|:|
Mouse   170 NSTYKFENRTDCWVTGWGAIGEDESLPSPNTLQEVQVAIINNSMC-NHMYKKPDFRTNIWGDMVC 233

  Fly   252 AGYVEQGGKDSCQGDSGGPMHVLGSGDAYQLAGIVSWGEGCAKPNAPGVYTRVGSFNDWI 311
            || ..:||||:|.||||||:........||: |:||||.||.:||.|||||.:....:||
Mouse   234 AG-TPEGGKDACFGDSGGPLACDQDTVWYQV-GVVSWGIGCGRPNRPGVYTNISHHYNWI 291

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	91/242 (38%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	92/243 (38%)
Prss21	NP_065233.2	Tryp_SPc	54..291	CDD:214473	91/242 (38%)
Prss21	NP_065233.2	Tryp_SPc	55..294	CDD:238113	92/243 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810