DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and si:dkeyp-93a5.3

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	XP_021326347.1	Gene:	si:dkeyp-93a5.3 / 571565	ZFINID:	ZDB-GENE-131127-100	Length:	328	Species:	Danio rerio

Alignment Length:	258	Identity:	92/258 - (35%)
Similarity:	129/258 - (50%)	Gaps:	22/258 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 CG--NINTRHRIVGGQETEVHEYPWMIMLMWFGNFYCGASLVNDQYALTAAHCVNGFYHRLITVR 136
            ||  |.....|||||.......:|||:.|......:||.||:|:|:.||||||:.......|.|.
Zfish    25 CGRPNPTLNPRIVGGVNATHGAWPWMVSLQGRYGHFCGGSLINNQWVLTAAHCIVDQTPSSIIVY 89

  Fly   137 LLEHNRQDSHVKIVDRRVSRVLIHPKYSTRNFDSDIALIRFNEPVRLGIDMHPVCMPTPSENY-A 200
            |.:.....:.|..:.|.:..::.||.||....|:||||::....|:....:.|:|:...:.|: .
Zfish    90 LGKWRSYVADVNSISRTIRHIIPHPSYSNITKDNDIALLQLTSTVQYTDYIKPICLADENSNFPR 154

  Fly   201 GQTAVVTGW---GALSEGG-----------PISDTLQEVEVPILSQEECRNSNYGESKITDNMIC 251
            |..:.|.||   |.|..||           |....|||.|:.:.|..:|.|..:|  :||.||||
Zfish   155 GTNSWVAGWGDIGVLGTGGIRGRTTVSVPLPHPGILQEAELKVYSNADCNNICHG--RITPNMIC 217

  Fly   252 AGYVEQGGKDSCQGDSGGPMHVLGSGDAYQLAGIVSWGEGCAKPNAPGVYTRVGSFNDWIAEN 314
            || ...|||.:..||||||:  :.....:..||::|.|.|||:||.|.|:.||..:..||..|
Zfish   218 AG-TRPGGKATFSGDSGGPL--MTKCSVWVQAGVLSHGYGCAQPNLPEVFIRVSEYKQWITGN 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	86/243 (35%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	87/245 (36%)
si:dkeyp-93a5.3	XP_021326347.1	Tryp_SPc	36..274	CDD:238113	85/242 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	191	1.000	Domainoid score	I3175
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	201	1.000	Inparanoid score	I3731
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm6349
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.960