Protein Alignment CG18735 and AZU1

DIOPT Version :10

• Sequence 1: NP_652645.1
• Gene: CG18735 / 59137
• FlyBaseID: FBgn0042098
• Length: 364
• Species: Drosophila melanogaster
• Sequence 2: NP_001691.1
• Gene: AZU1 / 566
• HGNCID: 913
• Length: 251
• Species: Homo sapiens
• Alignment Length: 238
• Identity: 61/238 - (25%)
• Similarity: 110/238 - (46%)
• Gaps: 34/238 - (14%)

  Fly    83 IVGGQETEVHEYPWMIMLMWFGNFYCGASLVNDQYALTAAHCVNGFYHRLITVRLLEHNRQDSHV 147
            ||||::....::|::..:...|..:||.:|::.::.:|||.|.......:.||.|..::     :
Human    27 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYD-----L 86

  Fly   148 KIVDRRVSRVLIHPKYSTRNFD-----SDIALIRFNEPVRLGIDMHPVCMPTPSEN---YAGQTA 204
            :..:|:..:.......|...:|     :|:.|::.:....|...:  ..:|.|.:|   .||...
Human    87 RRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSV--TILPLPLQNATVEAGTRC 149

  Fly   205 VVTGWGALSEGGPISDTLQEVEVPILSQEECRNSNYGESKITDNMICAGYVEQGGKDSCQGDSGG 269
            .|.|||:...||.:|...:.|.|.:..:::||.:|          :|.|.:.:.| ..|.||.|.
Human   150 QVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPNN----------VCTGVLTRRG-GICNGDGGT 203

  Fly   270 PMHVLGSGDAYQLAGIVSWGEG-CAKPNAPGVYTRVGSFNDWI 311
            |:  :..|.|:   |:.|:..| |.:  .|..:|||..|.|||
Human   204 PL--VCEGLAH---GVASFSLGPCGR--GPDFFTRVALFRDWI 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	61/238 (26%)
AZU1	NP_001691.1	Tryp_SPc	27..240	CDD:238113	61/238 (26%)
		Possesses antibiotic activity. /evidence=ECO:0000269|PubMed:8506327	46..70		8/23 (35%)