DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and tmprss13b

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	XP_005165399.1	Gene:	tmprss13b / 564693	ZFINID:	ZDB-GENE-090309-2	Length:	475	Species:	Danio rerio

Alignment Length:	319	Identity:	101/319 - (31%)
Similarity:	158/319 - (49%)	Gaps:	28/319 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LGDLACATPSLRSASDPEKILNNLAQLRQSSFLDWIQSILGPEVPAEWSSPAKR----ECAECSC 74
            :.|..|.....|.:.....:.:| :.:.||.....:.:|.| .|....|.|.::    :|  |.|
Zfish   169 IADQTCQQLGFRQSYSYGVVKSN-SPMFQSVNSQLVNNIQG-RVNTSSSCPDQQSVSLQC--CDC 229

  Fly    75 GNINTRHRIVGGQETEVHEYPWMIMLMWFGNFYCGASLVNDQYALTAAHCVNGFYHRLITVRLLE 139
            |......||:||.......:||...|.:.|...||.|||...:.:|||||    :.:..:...|.
Zfish   230 GRPPVSSRIIGGSVAAEGHWPWQASLHFQGKHSCGGSLVAPDFIITAAHC----FPKETSGSQLP 290

  Fly   140 HNRQ-----DSHVKIVD-RRVSRVLIHPKY--STRNFDSDIALIRFNEPVRLGIDMHPVCMPTPS 196
            .|.:     .|.:|:.. ..|..:::|.||  :|:|:  ||||::.|:|..   |:.|:|:|...
Zfish   291 SNWKVYIGFVSQLKLPSPYYVKEIILHEKYNPTTKNY--DIALLKLNKPAS---DVEPICLPVIG 350

  Fly   197 ENY-AGQTAVVTGWGALSEG-GPISDTLQEVEVPILSQEECRNSNYGESKITDNMICAGYVEQGG 259
            :.: ..:....||:|.:.:| ..:|.:|.||.|.::....|.:.|....:||:||.|||.: :||
Zfish   351 QTFPPAKQCWTTGFGVIRQGSNSVSTSLMEVTVSLIDSSVCNSPNVYNGEITENMQCAGDL-RGG 414

  Fly   260 KDSCQGDSGGPMHVLGSGDAYQLAGIVSWGEGCAKPNAPGVYTRVGSFNDWIAENTRDA 318
            |||||||||||:....:...:.|.|:.||||||.:.|.||||:.|..:..||....:.|
Zfish   415 KDSCQGDSGGPLACKSNDGQWFLTGVTSWGEGCGQVNRPGVYSDVAKYLMWIYSKMQQA 473

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	83/238 (35%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	84/240 (35%)
tmprss13b	XP_005165399.1	SRCR_2	147..230	CDD:295335	13/64 (20%)
		Tryp_SPc	237..466	CDD:214473	83/238 (35%)
		Tryp_SPc	238..469	CDD:238113	84/240 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm6379
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.910