DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and tmprss9

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	XP_021325244.1	Gene:	tmprss9 / 562051	ZFINID:	ZDB-GENE-050208-573	Length:	788	Species:	Danio rerio

Alignment Length:	352	Identity:	118/352 - (33%)
Similarity:	177/352 - (50%)	Gaps:	56/352 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 KILNNLAQLRQSSF-LDWIQSILGPEVPAEWSSPAKRECAE------CSCGNINTR----HRIVG 85
            :|.|::::...|:| .|..:.|..|....::.:    :|.:      ||||   ||    :||||
Zfish   177 EIGNDISKCPDSTFTCDNGECITKPNPECDYIT----DCTDGSDETFCSCG---TRPVMSNRIVG 234

  Fly    86 GQETEVHEYPWMIMLMWFGNFYCGASLVNDQYALTAAHCVNGFYHRLITVRLLEHNRQDSHVKIV 150
            |:.|...|:||.:.|...|...||||:||.::.::||||..           :|:|.:|....:.
Zfish   235 GENTRHGEFPWQVSLRLRGRHTCGASIVNSRWLVSAAHCFE-----------VENNPKDWTALVG 288

  Fly   151 DRRVS------------RVLIHPKYSTRNFDSDIALIRFNEPVRLGIDMHPVCMPTPSENYA-GQ 202
            ..:||            .:::.|||.....|||:.::....|::....:.|||:|:.|..:. ||
Zfish   289 ANQVSGAEAEAFIVNIKSLVMSPKYDPMTTDSDVTVLELETPLKFSHYVQPVCIPSSSHVFTPGQ 353

  Fly   203 TAVVTGWGALSE-GGPISDTLQEVEVPILSQEECRNSNYGESKITDNMICAGYVEQGGKDSCQGD 266
            ..:|:|||||:: ...:..|||:..|.|:..:.|..|:.....:|.||:|||:: ||..||||||
Zfish   354 NCIVSGWGALNQYTTEVPSTLQKAIVKIIDSKVCNKSSVYRGALTQNMMCAGFL-QGKVDSCQGD 417

  Fly   267 SGGPMHVLGSGDAYQLAGIVSWGEGCAKPNAPGVYTRVGSFNDWIAENTRDACSCAQPEAAGEPA 331
            ||||:....:...|.||||||||.|||:.|.||||:||....:||...|:.|     |.....|.
Zfish   418 SGGPLACEVAAGRYFLAGIVSWGVGCAQINKPGVYSRVTKLRNWIVSYTKTA-----PAFQENPT 477

  Fly   332 SPMETTEQGDQENTTANGAAEADPEVE 358
            .|..||       |.|:....|:|..|
Zfish   478 VPSVTT-------TEAHHVKAANPSSE 497

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	90/242 (37%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	91/244 (37%)
tmprss9	XP_021325244.1	SEA	52..146	CDD:307516
		LDLa	185..220	CDD:238060	6/38 (16%)
		Tryp_SPc	232..462	CDD:238113	89/241 (37%)
		LDLa	510..544	CDD:238060
		Tryp_SPc	557..783	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810