DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and masp2

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	NP_001116330.1	Gene:	masp2 / 560277	ZFINID:	ZDB-GENE-060130-154	Length:	684	Species:	Danio rerio

Alignment Length:	261	Identity:	95/261 - (36%)
Similarity:	141/261 - (54%)	Gaps:	29/261 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 CGNINTR-HRIVGGQETEVHEYPWMIMLMWFGNFYCGASLVNDQYALTAAHCVNGFYH------R 131
            ||....: .:::||:..|.:|.||.:|:.....|..||||::|.:.|||||.|..|..      |
Zfish   426 CGQPELKLSKVIGGENAEKNEIPWQVMIRMGTKFIGGASLLSDGWVLTAAHVVKSFEDSANLQLR 490

  Fly   132 LITVRLLEHNRQDSHVKIVDRRVSRVLIHPKY--STRNFDSDIALIRFNEPVRLGIDMHPVCMPT 194
            :.||:   |:..::.|.|    ..::.|||:|  ...||:.|||||:....|.:...:.|||:|.
Zfish   491 MGTVK---HHDNEAVVGI----PQKIFIHPQYHHDNVNFNHDIALIKLEYKVPVSKAVMPVCLPG 548

  Fly   195 PSENY---AGQTAVVTGWGALSEGGP--ISDTLQEVEVPILSQEECRN------SNYGESKITDN 248
            ..|.:   |.....|:|||..:...|  .|..|:.|.:|:.:..:|:.      ::.|:..:|:|
Zfish   549 REERFVLKANDVGKVSGWGVSNINTPALFSGNLKYVHLPVSNFNDCKTKYDSTVTSKGKLVVTEN 613

  Fly   249 MICAGYVEQGGKDSCQGDSGGPMHVLG-SGDAYQLAGIVSWGEGCAKPNAPGVYTRVGSFNDWIA 312
            |||||: .||||||||||||||..... ...::.:.||||||.|||:....||||:|.::..||.
Zfish   614 MICAGF-SQGGKDSCQGDSGGPFAFFDKQSKSWFIGGIVSWGHGCAQAGYYGVYTKVSNYLSWIE 677

  Fly   313 E 313
            |
Zfish   678 E 678

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	90/248 (36%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	93/251 (37%)
masp2	NP_001116330.1	CUB	24..130	CDD:214483
		EGF_CA	134..176	CDD:214542
		CUB	180..289	CDD:278839
		CCP	296..357	CDD:214478
		CCP	362..410	CDD:153056
		Tryp_SPc	435..676	CDD:214473	90/248 (36%)
		Tryp_SPc	436..679	CDD:238113	93/251 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910