DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and habp2

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	NP_001103843.2	Gene:	habp2 / 553472	ZFINID:	ZDB-GENE-030131-4721	Length:	546	Species:	Danio rerio

Alignment Length:	292	Identity:	92/292 - (31%)
Similarity:	145/292 - (49%)	Gaps:	49/292 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 PEVPAEWSSPAKRECAECSCGNIN-TRHRIVGGQETEVHEYPWMIMLMWFGNFY----------- 107
            ||.|.  ::|.|.|.::|.....: ...||.||:::....:||.      .:|.
Zfish   276 PEKPL--TTPTKLEFSDCGKAAFSMIAPRIFGGRKSLPEAHPWQ------ASFQVRPKGSNATFE 332

  Fly   108 --CGASLVNDQYALTAAHCVNGFYHRLITVRLLEHNRQDSHVKIVDRRVSRVLIHPKYSTRNFD- 169
              ||.:|::..:.||||||::......:.:..:...:.|...:.|:  |.::::|..| |..||
Zfish   333 HNCGGTLIDSCWILTAAHCIDENDEVRVELGGVNLEKDDPDKQFVE--VEKIIVHENY-TETFDA 394

  Fly   170 --SDIALIRF--------NEPVRLGIDMHPVCMPT---PSENYAGQTAVVTGWGALSEGGPISDT 221
              :||||::.        ||    ...:...|:||   |.    |....::|:||..:...:|..
Zfish   395 LYNDIALLKLKGRNGRCANE----SRSVRAACLPTDLFPE----GTRCTISGYGATEKHHGVSTQ 451

  Fly   222 LQEVEVPILSQEECRNSNYGESKITDNMICAGYVEQGGKDSCQGDSGGPMHVLGSGDAYQLAGIV 286
            |.:.:|.::||..|.:.|...:::.|:|:||||: ||..||||||||||: |....:.:.:.|:|
Zfish   452 LLDAKVLLISQSRCMSRNVYGNRMDDSMMCAGYM-QGKIDSCQGDSGGPL-VCKKDNIHYIYGVV 514

  Fly   287 SWGEGCAKPNAPGVYTRVGSFNDWIAENTRDA 318
            |||:.|.|.|.||||.||..|.|||.|..|.|
Zfish   515 SWGDSCGKKNKPGVYARVTKFIDWINEKMRTA 546

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	80/255 (31%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	81/257 (32%)
habp2	NP_001103843.2	EGF_CA	80..112	CDD:238011
		EGF_CA	158..190	CDD:238011
		KR	195..273	CDD:214527
		Tryp_SPc	302..539	CDD:214473	80/255 (31%)
		Tryp_SPc	303..542	CDD:238113	81/257 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910