DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and f10

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	NP_001015728.1	Gene:	f10 / 548445	XenbaseID:	XB-GENE-971433	Length:	464	Species:	Xenopus tropicalis

Alignment Length:	241	Identity:	86/241 - (35%)
Similarity:	137/241 - (56%)	Gaps:	23/241 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 RIVGGQETEVHEYPWMIMLMW-FGNFYCGASLVNDQYALTAAHCVNGF-YHRLITVRL---LEHN 141
            |||||:|....|.||..:|:. ....:||.::::.::.||||||:|.. |.:::...|   :...
Frog   227 RIVGGRECSQGECPWQALLVSDEDEGFCGGTILSREFILTAAHCMNQTKYFKVVVGELNTKISEG 291

  Fly   142 RQDSHVKIVDRRVSRVLIHPKYSTRNFDSDIALIRFNEPVRLGIDMHPVCMPTPSENYAGQT--- 203
            .:..|      :|.::::||::....:|.|||:|:..|.:....::.|.|:|.|  .:|.|.
Frog   292 TESIH------KVEKIIMHPRFVKSTYDYDIAVIKLKEAINFTENIIPACIPDP--EFADQVLMN 348

  Fly   204 ---AVVTGWGALSEGGPISDTLQEVEVPILSQEECRNSNYGESKITDNMICAGYVEQGGKDSCQG 265
               |:|:|:|.:.|.|..:.|||.::||.:.:..|:.|:  ...||:||.|||: :...||:|||
Frog   349 EPDAMVSGFGRIHERGRQASTLQMLQVPYIKRHSCKESS--TFAITENMFCAGF-DTEVKDACQG 410

  Fly   266 DSGGPMHVLGSGDAYQLAGIVSWGEGCAKPNAPGVYTRVGSFNDWI 311
            ||||| ||......|.:.||||||||||:....||||:|...:.|:
Frog   411 DSGGP-HVTPFKGTYFVTGIVSWGEGCARKGKFGVYTKVSKLHRWL 455

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	85/239 (36%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	85/240 (35%)
f10	NP_001015728.1	GLA	22..84	CDD:214503
		EGF_CA	85..121	CDD:238011
		FXa_inhibition	128..163	CDD:373209
		Tryp_SPc	228..456	CDD:238113	85/240 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910