DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG18735 and Corin

DIOPT Version :9

Sequence 1:NP_652645.1 Gene:CG18735 / 59137 FlyBaseID:FBgn0042098 Length:364 Species:Drosophila melanogaster
Sequence 2:NP_058565.2 Gene:Corin / 53419 MGIID:1349451 Length:1113 Species:Mus musculus


Alignment Length:330 Identity:104/330 - (31%)
Similarity:147/330 - (44%) Gaps:54/330 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly    14 LGDLACATPSLRSASDPEKILNNLAQLRQSSFLDW-------IQSILGPEVPAEWSSPAKRE--- 68
            |..|||....|...|..:.|.....|.....:.:|       :|.:|    ....|.|::.|   
Mouse   790 LSQLACKQMGLGEPSVTKLIPGQEGQQWLRLYPNWENLNGSTLQELL----VYRHSCPSRSEISL 850

  Fly    69 -CAECSCGN---INTRHRIVGGQETEVHEYPWMIMLMWF-GNFYCGASLVNDQYALTAAHCVNGF 128
             |::..||.   .....||:||:.:....:||...|... ....||..|:..::.||.|||..| 
Mouse   851 LCSKQDCGRRPAARMNKRILGGRTSRPGRWPWQCSLQSEPSGHICGCVLIAKKWVLTVAHCFEG- 914

  Fly   129 YHRLITVRLLEHNRQDSHV-KIV--------------DRRVSRVLIHPKYSTRNFDSDIALIRFN 178
                         |:|:.| |:|              .|.|..:|:||:||....|.||:::..:
Mouse   915 -------------REDADVWKVVFGINNLDHPSGFMQTRFVKTILLHPRYSRAVVDYDISVVELS 966

  Fly   179 EPVRLGIDMHPVCMPTPSENYAGQT-AVVTGWGALSEGGPISDTLQEVEVPILSQEECRNSNYGE 242
            :.:.....:.|||:|:|.|.....| ..:||||.:....|..  |||.||.|:..|:|: |.:..
Mouse   967 DDINETSYVRPVCLPSPEEYLEPDTYCYITGWGHMGNKMPFK--LQEGEVRIIPLEQCQ-SYFDM 1028

  Fly   243 SKITDNMICAGYVEQGGKDSCQGDSGGPMHVLGSGDAYQLAGIVSWGEGC-AKPNAPGVYTRVGS 306
            ..||:.|||||| |.|..|||.||||||:.....|..:.|.|:.|||..| :|...||||:.|..
Mouse  1029 KTITNRMICAGY-ESGTVDSCMGDSGGPLVCERPGGQWTLFGLTSWGSVCFSKVLGPGVYSNVSY 1092

  Fly   307 FNDWI 311
            |..||
Mouse  1093 FVGWI 1097

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG18735NP_652645.1 Tryp_SPc 82..311 CDD:214473 85/246 (35%)
Tryp_SPc 83..314 CDD:238113 86/247 (35%)
CorinNP_058565.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 176..202
CRD_corin_1 202..331 CDD:143554
LDLa 337..372 CDD:238060
LDLa 374..408 CDD:238060
Ldl_recept_a 415..445 CDD:278486
LDLa 455..482 CDD:238060
CRD_corin_2 522..643 CDD:143579
Ldl_recept_a 648..682 CDD:278486
LDLa <695..720 CDD:238060
LDLa 723..757 CDD:238060
SR 758..853 CDD:214555 14/66 (21%)
Tryp_SPc 868..1097 CDD:214473 85/246 (35%)
Tryp_SPc 869..1100 CDD:238113 86/247 (35%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.910

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