DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18735 and Prss53

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	XP_006230384.1	Gene:	Prss53 / 499270	RGDID:	1566127	Length:	591	Species:	Rattus norvegicus

Alignment Length:	366	Identity:	83/366 - (22%)
Similarity:	140/366 - (38%)	Gaps:	84/366 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 LRQSSFLDWIQSIL--GPEVPAEWSSPAKRECAECSCGNINTRHRIVGGQETEVHEYPWMIMLMW 102
            :|||    |...:|  |..:..|....|:|.|.:...|....:.     ..|...|:||...:..
  Rat     1 MRQS----WGPELLIVGAVIVIEGLQAAQRACGQRGPGPPEPQE-----GNTLPGEWPWQASVRR 56

  Fly   103 FGNFYCGASLVNDQYALTAAHCVNGFYHRLITVRL------LEHNRQDSHVKIVDRRVSRVLIHP 161
            .|...|..|||.|.:.||||||    :.::.|..|      |...:|:......:......|..|
  Rat    57 QGVHICSGSLVADTWVLTAAHC----FEKMATAELSSWSVVLGSLKQEGLSPGAEEVGVAALQLP 117

  Fly   162 K-YSTRNFDSDIALIRFNEPVRLGIDMH-PVCMPTPSENYA-GQTAVVTGWGALSEGG------- 216
            | |:..:..||:||::...|:     :| .:|:|.|:.::. |.:...|||...:..|
  Rat   118 KAYNHYSQGSDLALLQLTHPI-----VHTTLCLPQPTHHFPFGASCWATGWDQNTSDGKYCPRHK 177

  Fly   217 ------------------------------PISDTLQEVEVPILSQEECRNSNYGE-------SK 244
                                          |:|.||:.:.:.::|:..| |..|..       :.
  Rat   178 SRESQTGSVLTVLALCSHCVSELDSTLSPLPVSRTLRNLRLRLISRPTC-NCLYNRLHQRLLANP 241

  Fly   245 ITDNMICAGYVEQGGKDSCQGDSGGPMHVLGSGDAYQLAGIVSWGEGCAKPNAPGVYTRVGSFND 309
            ....|:|.| .:.|.:..||||||||:........:...||:|:...||:.:.|.:.|.:.:.:.
  Rat   242 ARSGMLCGG-AQPGVQGPCQGDSGGPVMCREPDGHWVQVGIISFTSNCAQEDTPVLLTDMAAHSS 305

  Fly   310 WIAENTRDACSCAQPEAAGEPASPMETTEQGDQENTTANGA 350
            |:..:...|....|     :|.    ..:..|:.:..|.|:
  Rat   306 WLQAHVDRAAFLVQ-----DPG----VVKMSDENSCVACGS 337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	65/281 (23%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	66/283 (23%)
Prss53	XP_006230384.1	Tryp_SPc	45..310	CDD:238113	65/275 (24%)
Prss53	XP_006230384.1	Tryp_SPc	341..561	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910