DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and Tmprss11f

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	XP_038948844.1	Gene:	Tmprss11f / 498345	RGDID:	1560675	Length:	459	Species:	Rattus norvegicus

Alignment Length:	296	Identity:	101/296 - (34%)
Similarity:	148/296 - (50%)	Gaps:	53/296 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 ILNNLAQLRQSSFLDWIQSILGPEVPAEWSSPAKRECAECSCGNINTRHRIVGGQETEVH-EYPW 96
            :||:...:|.||          ..:|...||               |..|||.|:||.:. |:||
  Rat   202 LLNSRCGIRMSS----------SNIPLPASS---------------TTERIVQGRETAMEGEWPW 241

  Fly    97 MIMLMWFG-NFYCGASLVNDQYALTAAHCVNGFYHRLITVRLLEHNRQDSH----------VKIV 150
            ...|...| ...|||:|:::.:.||||||   |:          .||..|.          ..:|
  Rat   242 QASLQLIGAGHQCGATLISNTWLLTAAHC---FW----------KNRDPSKWIATFGTTITPPLV 293

  Fly   151 DRRVSRVLIHPKYSTRNFDSDIALIRFNEPVRLGIDMHPVCMPTPSENYAGQTAV-VTGWGALSE 214
            .|.|.|::||.:|...:.::||||.:....|.....:..||:|..|.....:|:| |||:|::.:
  Rat   294 KRSVGRIIIHEEYHRDSNENDIALAQLTSRVEFSNVVQRVCLPDSSMKLPPKTSVFVTGFGSIVD 358

  Fly   215 GGPISDTLQEVEVPILSQEECRNSNYGESKITDNMICAGYVEQGGKDSCQGDSGGPMHVLGSGDA 279
            .||..:.|::..|..:..:.|...:..:..||..|:|||::| |..|:|:||||||: |..:.|.
  Rat   359 DGPTQNKLRQARVETIGSDVCNQKDVYDGLITPGMLCAGFME-GKVDACKGDSGGPL-VYDNRDI 421

  Fly   280 YQLAGIVSWGEGCAKPNAPGVYTRVGSFNDWIAENT 315
            :.:.||||||:.||.||.|||||||..:.||||..|
  Rat   422 WYIVGIVSWGQSCALPNKPGVYTRVSKYRDWIASKT 457

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	88/241 (37%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	90/243 (37%)
Tmprss11f	XP_038948844.1	SEA	80..185	CDD:396113
Tmprss11f	XP_038948844.1	Tryp_SPc	227..456	CDD:238113	90/243 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910