DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and prss27

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	XP_031749235.1	Gene:	prss27 / 496619	XenbaseID:	XB-GENE-5744470	Length:	724	Species:	Xenopus tropicalis

Alignment Length:	351	Identity:	116/351 - (33%)
Similarity:	171/351 - (48%)	Gaps:	51/351 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 SASDPEKILNNLAQLRQSSFLDWIQSILGPEVP------------AEWSSPAKRECAECSCGNIN 78
            |.::.:|.|.::.||          |::||..|            |.::..|    ....||...
Frog   365 SRAEGQKSLPSVTQL----------SLIGPMDPPSMMLRIISLLLAGFAVTA----ISTGCGQPA 415

  Fly    79 TRHRIVGGQETEVHEYPWMIMLMWFGNFYCGASLVNDQYALTAAHCVNGFY-----HRLITVRLL 138
            ...|||||......|:||.:.:::..:..||.|||:..:.::||||....|     ..|:....|
Frog   416 FSDRIVGGNNAVFGEWPWQVSIVYQNSHICGGSLVSSNWVVSAAHCFPRSYKIENMQVLLGCFAL 480

  Fly   139 EHNRQDSHVKIVDRRVSRVLIHPKYSTRNFDSDIALIRFNEPVRLGIDMHPVCMPTPSENY-AGQ 202
            .:...|:    |..||.||:.:|.|:......|||::....||.....:.|:|:|..:|:: :|:
Frog   481 MNLTSDA----VIIRVKRVITYPLYTGEGSSGDIAMVEMESPVTYSSYILPICIPLTNEDFPSGK 541

  Fly   203 TAVVTGWGALSEGGPISD--TLQEVEVPILSQEEC-----RNS--NYGESKITDNMICAGYVEQG 258
            ...|||||.:.....:|.  .|||||||:::...|     .||  |.....:.|:||||||.| |
Frog   542 MCWVTGWGNIQSDVSLSPPYPLQEVEVPLVNASSCDTMYHYNSDLNPATQLVHDDMICAGYPE-G 605

  Fly   259 GKDSCQGDSGGPMHVLGSGDAYQLAGIVSWGEGCAKPNAPGVYTRVGSFNDWIAE----NTRDAC 319
            .||:||||||||: ...||:.:.|.||||||:|||:||.|||||:|.||:.||.:    |.....
Frog   606 QKDACQGDSGGPL-ACKSGNYWFLTGIVSWGDGCAQPNRPGVYTKVSSFSSWINQYLVLNVSVTT 669

  Fly   320 SCAQPEAAGEPASPMETTEQGDQENT 345
            ......:....:|..|.....|.:|:
Frog   670 KTPHSISLANSSSTKEAVTNTDYKNS 695

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	96/243 (40%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	97/249 (39%)
prss27	XP_031749235.1	Tryp_SPc	34..271	CDD:238113
prss27	XP_031749235.1	Tryp_SPc	420..659	CDD:238113	97/244 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	183	1.000	Inparanoid score	I3837
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D380103at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.970