DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and masp2

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	NP_001011037.1	Gene:	masp2 / 496446	XenbaseID:	XB-GENE-1007491	Length:	687	Species:	Xenopus tropicalis

Alignment Length:	252	Identity:	91/252 - (36%)
Similarity:	133/252 - (52%)	Gaps:	23/252 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 RIVGGQETEVHEYPWMIMLMWFGNFYCGASLVNDQYALTAAHCVNGFYHRL--ITVRLLEHNRQD 144
            |||||:...|.|:||.:.:. ..|...|.:|:.|.:.|||||.|.. |..|  |.:::...:.||
Frog   443 RIVGGEFANVGEFPWQVFIN-ANNERGGGALLLDNWILTAAHVVYS-YDDLSSILIKMGFLSTQD 505

  Fly   145 SHVKIVDRRVSRVLIHPKYSTRNFDSDIALIRFNEPVRLGID-MHPVCMPTPSENY-------AG 201
            |:  .:......|.||..|...::::|||||:....|.|..: :..:|:||..::|       ..
Frog   506 SN--YIRGWPEAVFIHEGYKPGHYNNDIALIKLKNKVPLSEESILGICLPTKEKSYHISHKDDDN 568

  Fly   202 QTAVVTGWGALSEGGPISDTLQEVEVPILSQEECRNSNYGESK----ITDNMICAGYVEQGGKDS 262
            ...:|.||| |:|....|..|:.|||.|:....|: :.|.:..    :|:||||||: |.|.|||
Frog   569 HVGLVAGWG-LTEAQRSSRKLRFVEVNIVDHSTCK-AEYAKLDAQYIVTENMICAGF-EIGVKDS 630

  Fly   263 CQGDSGGPMHVLGS-GDAYQLAGIVSWGEGCAKPNAPGVYTRVGSFNDWIAENTRDA 318
            |.|||||.:..:.: ...:.:.||||||.||......||||:|.::.||| |.|..|
Frog   631 CAGDSGGALAFMNAESKKWFVGGIVSWGVGCGVARQYGVYTKVTNYLDWI-EKTIQA 686

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	86/243 (35%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	87/245 (36%)
masp2	NP_001011037.1	CUB	30..139	CDD:238001
		FXa_inhibition	145..180	CDD:317114
		CUB	184..294	CDD:238001
		CCP	299..361	CDD:153056
		CCP	365..430	CDD:153056
		Tryp_SPc	443..680	CDD:214473	86/243 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910