DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and tll1

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	NP_001008039.1	Gene:	tll1 / 493401	XenbaseID:	XB-GENE-479941	Length:	495	Species:	Xenopus tropicalis

Alignment Length:	273	Identity:	61/273 - (22%)
Similarity:	89/273 - (32%)	Gaps:	113/273 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 HLLLI-----LATAL---GDLACATPSLRSASDPEKILNNLAQLRQSSFLDWIQSILGPEVPAEW 61
            ||:|:     |:..|   |.|  .||..:...||..  |||       :.|.::        |..
Frog     6 HLILLFCLMGLSLTLPLSGTL--PTPKSQDGKDPAD--NNL-------YTDIMK--------ANQ 51

  Fly    62 SSPAKR--------------ECAEC-----SCGNINTRHRI--------VGGQETEVHEYPWMIM 99
            .|...|              .|.||     |.|.:...:.:        |....|.:.||..:..
Frog    52 KSKKLRIHGDIALKTDRNAINCTECLWPKSSDGFVYVPYTVSSDYSQDEVNAITTAMKEYEGLTC 116

  Fly   100 LM---WFG-----------------NFYCGASLVN-----DQYALTAAHCVN---GFYHRLITVR 136
            :.   |.|                 .:|.|:..|:     ..|.....|.:|   ||||
Frog   117 VQFTPWTGEDDYLAIQSLDGCWSYIGYYGGSQAVSLLKGFCAYNGGVQHELNHALGFYH------ 175

  Fly   137 LLEHNR--QDSHVKIVDRRVSRVLIHPKYSTRNFDSDIALIRFNEPVRLGID------MHPVCMP 193
              ||||  :|.:|.|:.:.:|     |: :..|||.    |..|   .||:|      :|  ...
Frog   176 --EHNRSDRDDYVTIMYQYIS-----PE-NIGNFDK----ISTN---NLGVDYDYSSILH--YAG 223

  Fly   194 TPSENYAGQTAVV 206
            ....|.:||..:|
Frog   224 NAFSNTSGQNTIV 236

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	38/169 (22%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	38/168 (23%)
tll1	NP_001008039.1	ZnMc_hatching_enzyme	83..265	CDD:239810	39/177 (22%)
		CUB	269..379	CDD:238001
		CUB	382..494	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910