Protein Alignment CG18735 and ACR

DIOPT Version :10

• Sequence 1: NP_652645.1
• Gene: CG18735 / 59137
• FlyBaseID: FBgn0042098
• Length: 364
• Species: Drosophila melanogaster
• Sequence 2: NP_001088.2
• Gene: ACR / 49
• HGNCID: 126
• Length: 421
• Species: Homo sapiens
• Alignment Length: 275
• Identity: 92/275 - (33%)
• Similarity: 137/275 - (49%)
• Gaps: 29/275 - (10%)

  Fly    63 SPAKRECAECS--CG-----NINTRHRIVGGQETEVHEYPWMIMLMWF---GNFY--CGASLVND 115
            |...::.|.|.  ||     |.....|||||:..:...:|||:.|..|   .:.|  ||.||:|.
Human    16 SVVAKDNATCDGPCGLRFRQNPQGGVRIVGGKAAQHGAWPWMVSLQIFTYNSHRYHTCGGSLLNS 80

  Fly   116 QYALTAAHCVNGFYH----RLI--TVRLLEHNRQDSHVKIVDRRVSRVLIHPKYSTRNFDSDIAL 174
            ::.||||||..|..:    ||:  ...:...|.:.....:.:|.|.:::||.||::....:||||
Human    81 RWVLTAAHCFVGKNNVHDWRLVFGAKEITYGNNKPVKAPLQERYVEKIIIHEKYNSATEGNDIAL 145

  Fly   175 IRFNEPVRLGIDMHPVCMP-----TPSENYAGQTAVVTGWGALSEGGP-ISDTLQEVEVPILSQE 233
            :....|:..|..:.|.|:|     .|.   ..|:..|.|||.:.|..| .|..|.|..|.::..:
Human   146 VEITPPISCGRFIGPGCLPHFKAGLPR---GSQSCWVAGWGYIEEKAPRPSSILMEARVDLIDLD 207

  Fly   234 ECRNSNYGESKITDNMICAGYVEQGGKDSCQGDSGGPMHVLGSGD-AYQLAGIVSWGEGCAKPNA 297
            .|.::.:...::....:|||| ..|..|:||||||||:....|.: ||.:.||.|||.|||:...
Human   208 LCNSTQWYNGRVQPTNVCAGY-PVGKIDTCQGDSGGPLMCKDSKESAYVVVGITSWGVGCARAKR 271

  Fly   298 PGVYTRVGSFNDWIA 312
            ||:||....:.:|||
Human   272 PGIYTATWPYLNWIA 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	85/248 (34%)
ACR	NP_001088.2	Tryp_SPc	42..285	CDD:214473	83/246 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	297..316
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	327..383
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	397..421