DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and AgaP_AGAP012269

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	XP_001238284.2	Gene:	AgaP_AGAP012269 / 4577485	VectorBaseID:	AGAP012269	Length:	649	Species:	Anopheles gambiae

Alignment Length:	263	Identity:	69/263 - (26%)
Similarity:	123/263 - (46%)	Gaps:	32/263 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 SCG--NINTRHRIVGGQETEVHEYPWMIMLMWFG----NFYCGASLVNDQYALTAAHC---VNGF 128
            :||  .:.|.|.:..|.:.:...:||...:....    ::.||.|::::...||||||   |||
Mosquito    29 TCGKRRVKTIHLVHNGIDAKPGHWPWHAAIFHRKGDQMDYACGGSIIDENTILTAAHCVFLVNG- 92

  Fly   129 YHRLITVRLLEHNRQDSHVK-----IVDRRVSRVLIHPKYSTRNFDSDIALIRFNEPVRLGIDMH 188
               |:.|..:..:....|:|     :.:..|..:::||.|::..|.:|||||:....:.:...:.
Mosquito    93 ---LLPVSRISVHLGRVHLKEVSEFVQEHTVQELIVHPGYNSSRFVNDIALIKLTGSITMSEFVQ 154

  Fly   189 PVCMPTPSEN---YAGQTAVVTGWGALSEGGPISDTLQEVEVPILSQEECRNSN--YGESKITDN 248
            |||:.|..:|   ..|:|..:.|:| |:|...:|:.|::..:.::....|..|:  ...:::|..
Mosquito   155 PVCLWTMDKNQELIVGKTGTLVGFG-LNEQDVVSEQLKQASIGVVDALTCIKSDRLSFANQLTAE 218

  Fly   249 MICAGYVEQGGKDSCQGDSGGPMHVLGSGDAYQLAGIVSW-----GEGCAKPNAPGVYTRVGSFN 308
            |.|.|  .|....:|.|||||.:.....|..: :.|:||:     ..|...|:....|..|..:.
Mosquito   219 MFCGG--GQSNVSACNGDSGGGLFFNVEGKWF-VRGVVSFIPVRQRTGLCDPSKYTAYADVAKYL 280

  Fly   309 DWI 311
            .||
Mosquito   281 GWI 283

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	63/250 (25%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	65/251 (26%)
AgaP_AGAP012269	XP_001238284.2	Tryp_SPc	41..285	CDD:238113	65/251 (26%)
		Tryp_SPc	43..283	CDD:214473	63/247 (26%)
		Tryp_SPc	418..636	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910