DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and AgaP_AGAP004571

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	XP_313875.2	Gene:	AgaP_AGAP004571 / 4576898	VectorBaseID:	AGAP004571	Length:	324	Species:	Anopheles gambiae

Alignment Length:	330	Identity:	151/330 - (45%)
Similarity:	192/330 - (58%)	Gaps:	14/330 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MCNFHLLLILATAL--GDLACATPSLRSASDPEKILNNLAQLRQSSFLDWIQSILG---PEVPAE 60
            |....||::|...|  ||   |:..|::....|.:........:.|.:|.::.|.|   ...|..
Mosquito     2 MLEVPLLMLLMVGLLAGD---ASGKLQAQGKYEMLATPNKNTDERSIVDNMKMIFGGGSNRAPIH 63

  Fly    61 WSSPAKRECAECSCGNINTRHRIVGGQETEVHEYPWMIMLMWFGNFYCGASLVNDQYALTAAHCV 125
             .:|:  ....|.||..|...||||||.|.|:|:|||..|.:|..||||..|:||:|.|||||||
Mosquito    64 -DTPS--SACSCRCGERNDASRIVGGQATGVNEFPWMARLSYFNRFYCGGMLINDRYVLTAAHCV 125

  Fly   126 NGFYHRLITVRLLEHNRQDSHVKIVDRRVSRVLIHPKYSTRNFDSDIALIRFNEPVRLGIDMHPV 190
            .||...:|.|...||||.|..|:...|.|.|. |..|:|..|||:||||:|.|:.|.:...:.|:
Mosquito   126 KGFMWFMIKVTFGEHNRCDDSVRPETRFVLRA-IAQKFSFLNFDNDIALLRLNDRVPITDFIRPI 189

  Fly   191 CMPT-PSENYAGQTAVVTGWGALSEGGPISDTLQEVEVPILSQEEC-RNSNYGESKITDNMICAG 253
            |:|: ||..|.|.....||||.|.|.|..|..|||||||:||.|.| ..:||..|.|||||:|||
Mosquito   190 CLPSDPSNAYVGTNGTATGWGTLKEDGKPSCILQEVEVPVLSNEVCSTQTNYTASMITDNMLCAG 254

  Fly   254 YVEQGGKDSCQGDSGGPMHVLGSGDAYQLAGIVSWGEGCAKPNAPGVYTRVGSFNDWIAENTRDA 318
            |:..|.|||||||||||:........|:|.|:||||.|||:|..|||||||..:.|||.||::|.
Mosquito   255 YLGVGEKDSCQGDSGGPLIAEREDKRYELIGVVSWGNGCARPYYPGVYTRVTRYLDWIRENSKDG 319

  Fly   319 CSCAQ 323
            |.|::
Mosquito   320 CFCSE 324

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	124/230 (54%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	125/232 (54%)
AgaP_AGAP004571	XP_313875.2	Tryp_SPc	82..312	CDD:214473	124/230 (54%)
AgaP_AGAP004571	XP_313875.2	Tryp_SPc	83..315	CDD:238113	125/232 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D19085at50557
OrthoFinder	1	1.000	-	-		FOG0001240
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11
TreeFam	0	0.000	Not matched by this tool.
	4	3.920