DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and AgaP_AGAP012777

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	XP_001230468.2	Gene:	AgaP_AGAP012777 / 4397664	VectorBaseID:	AGAP012777	Length:	465	Species:	Anopheles gambiae

Alignment Length:	173	Identity:	47/173 - (27%)
Similarity:	84/173 - (48%)	Gaps:	14/173 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   149 IVDRRVSRVLIHPKYSTRNFDSDIALIRFNEPVRLGIDMHPVCMPTPSEN---YAGQTAVVTGWG 210
            :.:..|..:::||.|::..|.:|||||:..|.:.:...:.|||:.|..:|   ..|:|..:.|:|
Mosquito     8 VQEHTVQELIVHPGYNSSRFVNDIALIKLTESITMSEFVQPVCLWTMDKNQELIVGKTGTLVGFG 72

  Fly   211 ALSEGGPISDTLQEVEVPILSQEECRNSN--YGESKITDNMICAGYVEQGGKDSCQGDSGGPMHV 273
             |:|...:|:.|::..:.::....|..|:  ...:::|..|.|.|  .|....:|.|||||.:..
Mosquito    73 -LNEQDVVSEQLKQASIGVVDALTCIKSDRLSFANQLTAEMFCGG--GQSNVSACNGDSGGGLFF 134

  Fly   274 LGSGDAYQLAGIVSW-----GEGCAKPNAPGVYTRVGSFNDWI 311
            ...|..: :.|:||:     ..|...|:....|..|..:..||
Mosquito   135 NVEGKWF-VRGVVSFIPVRQRTGLCDPSKYTAYADVAKYLGWI 176

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	45/171 (26%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	47/173 (27%)
AgaP_AGAP012777	XP_001230468.2	Tryp_SPc	<1..178	CDD:238113	47/173 (27%)
		Tryp_SPc	<4..176	CDD:214473	45/171 (26%)
		Tryp_SPc	219..458	CDD:214473
		Tryp_SPc	219..458	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910