Protein Alignment CG18735 and KLK12

DIOPT Version :10

• Sequence 1: NP_652645.1
• Gene: CG18735 / 59137
• FlyBaseID: FBgn0042098
• Length: 364
• Species: Drosophila melanogaster
• Sequence 2: NP_062544.1
• Gene: KLK12 / 43849
• HGNCID: 6360
• Length: 254
• Species: Homo sapiens
• Alignment Length: 240
• Identity: 82/240 - (34%)
• Similarity: 114/240 - (47%)
• Gaps: 25/240 - (10%)

  Fly    82 RIVGGQETEVHEYPWMIMLMWFGNFYCGASLVNDQYALTAAHCVNGFYHRLITVRLLEHNRQDSH 146
            :|..|.|...:..||.:.|....:..||..|::.::.||||||....|    .|||.||:.....
Human    21 KIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAHCSGSRY----WVRLGEHSLSQLD 81

  Fly   147 VKIVDRRVSRVLIHPKY--STRNFDSDIALIRFNEPVRLGIDMHPVCMPTPSENYAGQTAVVTGW 209
            .....|.....:.||.|  ::.:.:.|:.|:|...|||:...:.|:.:|..... ||....|:||
Human    82 WTEQIRHSGFSVTHPGYLGASTSHEHDLRLLRLRLPVRVTSSVQPLPLPNDCAT-AGTECHVSGW 145

  Fly   210 GALSE-GGPISDTLQEVEVPILSQEECRNSNYGESKITDNMICAGYVEQGGKDSCQGDSGGPMHV 273
            |..:. ..|..|.||.:.:.|:|...|.....|  :||.||:|||.|.  |:|:||||||||: |
Human   146 GITNHPRNPFPDLLQCLNLSIVSHATCHGVYPG--RITSNMVCAGGVP--GQDACQGDSGGPL-V 205

  Fly   274 LGSGDAYQLAGIVSWGE--GCAKPNAPGVY------TRVGSFNDW 310
            .|.    .|.|:||||.  .|.:...||||      |.||....|
Human   206 CGG----VLQGLVSWGSVGPCGQDGIPGVYTYICNSTLVGLGTSW 246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	82/239 (34%)
KLK12	NP_062544.1	Tryp_SPc	22..236	CDD:238113	78/227 (34%)