DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and Tmprss11c

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	NP_001025468.1	Gene:	Tmprss11c / 435845	MGIID:	3521861	Length:	431	Species:	Mus musculus

Alignment Length:	264	Identity:	93/264 - (35%)
Similarity:	134/264 - (50%)	Gaps:	24/264 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 PAKRECAECSCGN---INTRHRIVGGQETEVHEYPWMIMLMWFGNFYCGASLVNDQYALTAAHCV 125
            |...:.....||.   |:..|::.|||:.|..|:||...|.......|||:|:::.:.:|||||.
Mouse   178 PIAEDLLNTCCGRRTIIHRGHKVAGGQDAEEGEWPWQASLQQNSVHRCGATLISNYWLITAAHCF 242

  Fly   126 NGFYHRLITVRLLEHNRQDSHVKI--------VDRRVSRVLIHPKYSTRNFDSDIALIRFNEPVR 182
                       :...|.:|..|..        ..|.|..::||..||....|:|||::|.:.||.
Mouse   243 -----------IRAANPKDWKVSFGFLLSKPQAPRAVKNIIIHENYSYPAHDNDIAVVRLSSPVL 296

  Fly   183 LGIDMHPVCMPTPSENY-AGQTAVVTGWGALSEGGPISDTLQEVEVPILSQEECRNSNYGESKIT 246
            ...::...|:|..::.: .....||||||.|...|...:.||:.:|.|:..:.|.:.......||
Mouse   297 YESNIRRACLPEATQKFPPNSDVVVTGWGTLKSDGDSPNILQKGKVKIIDNKTCNSGKAYGGMIT 361

  Fly   247 DNMICAGYVEQGGKDSCQGDSGGPMHVLGSGDAYQLAGIVSWGEGCAKPNAPGVYTRVGSFNDWI 311
            ..|:|||:: :|..|:||||||||:....|...:.||||||||:.||.||.|||||||..:.|||
Mouse   362 PGMMCAGFL-KGRVDACQGDSGGPLVSEDSKGIWFLAGIVSWGDECALPNKPGVYTRVTYYRDWI 425

  Fly   312 AENT 315
            ...|
Mouse   426 TSKT 429

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	85/237 (36%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	87/239 (36%)
Tmprss11c	NP_001025468.1	SEA	62..157	CDD:279699
		Tryp_SPc	199..425	CDD:214473	85/237 (36%)
		Tryp_SPc	200..428	CDD:238113	87/239 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	179	1.000	Inparanoid score	I3995
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.960