DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and proca

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	NP_956650.1	Gene:	proca / 393327	ZFINID:	ZDB-GENE-060824-5	Length:	434	Species:	Danio rerio

Alignment Length:	270	Identity:	95/270 - (35%)
Similarity:	145/270 - (53%)	Gaps:	33/270 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 RECA---ECSCGNIN-------------TRHRIVGGQETEVHEYPWM-IMLMWFGNFYCGASLVN 114
            |:|.   :.|||.|.             .:..::||...:..|.||. ::|...|.|:||..|::
Zfish   163 RKCTPKNDASCGQIRIPKSAYANKPKPVLQPWVMGGNVGKRGESPWQALILNHLGRFHCGGVLID 227

  Fly   115 DQYALTAAHCVNGFYHRLITVRLLEHNRQDSHVKIVDRRVSRVLIHPKYSTRNFDSDIALIRFNE 179
            :.:.||||||:.  .....:|||.::.|.......|...|.:.:.||:|:....|:||||:|.:.
Zfish   228 ENWVLTAAHCLE--TSSKFSVRLGDYQRFKFEGSEVTLPVKQHISHPQYNPITVDNDIALLRLDG 290

  Fly   180 PVRLGIDMHPVCMPTPSENYA-------GQTAVVTGWGALSEGG-PISDTLQEVEVPILSQEECR 236
            ||:....:.|.|:  ||...|       |...::||||..::.. ..:.||..||:||:..:||
Zfish   291 PVKFSTYILPACL--PSLELAKRMLHRNGTVTIITGWGKNNQSATSYNSTLHYVELPIVDNKEC- 352

  Fly   237 NSNYGESKITDNMICAGYVEQGGKDSCQGDSGGPMHVLGSGDAYQLAGIVSWGEGCAKPNAPGVY 301
             |.:..:.::|||:|||.:.| .||:|:|||||||..| ..|.:.|.|:|||||||.:.:..|:|
Zfish   353 -SRHMMNNLSDNMLCAGVLGQ-VKDACEGDSGGPMMTL-FHDTWFLVGLVSWGEGCGQRDKLGIY 414

  Fly   302 TRVGSFNDWI 311
            |:|.|:.|||
Zfish   415 TKVASYLDWI 424

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	87/237 (37%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	89/238 (37%)
proca	NP_956650.1	GLA	23..84	CDD:214503
		EGF_CA	85..119	CDD:238011
		FXa_inhibition	128..165	CDD:291342	1/1 (100%)
		Tryp_SPc	195..427	CDD:238113	89/238 (37%)
		Tryp_SPc	197..424	CDD:214473	87/234 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910