DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18735 and ovch1

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	NP_956439.2	Gene:	ovch1 / 393114	ZFINID:	ZDB-GENE-040426-834	Length:	556	Species:	Danio rerio

Alignment Length:	386	Identity:	116/386 - (30%)
Similarity:	184/386 - (47%)	Gaps:	86/386 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 CNFHLLLILATALGDLACATPSLRSASDPEKILNN----LAQLRQSSFLDWIQSILGPEVPAEWS 62
            |.|.|:|.|.....|      |..|:.:.:.||:.    ||.:|  ||:        ||...|.|
Zfish     7 CLFILILTLKWTKAD------SDASSFETDCILDKGCDVLAGIR--SFV--------PEDEVEES 55

  Fly    63 SPAKRECAECSCGNINTRHRIVGGQETEVHEYPWMIMLMWFGNFYCGASLVNDQYALTAAHCVNG 127
                               ||:||:|...|.:||.:.|.:.....||.::::..:.:||.||...
Zfish    56 -------------------RIIGGKEAWAHSWPWQVSLQYNDVPTCGGAILDQLWVITAGHCFKR 101

  Fly   128 F-----YHRLITVRLLEHNRQDSHVKIVDRRVSRVLIHPKYSTRNFDSDIALIRFNEP------V 181
            :     ::.::.:..|::..:.|...|   :|.::..|..|:.:..::||||::...|      |
Zfish   102 YKKPSMWNAVVGLHNLDNANESSRESI---QVQKIFSHKNYNQKTNENDIALLKLQSPLVFSKFV 163

  Fly   182 R-LGI---DMHPVCMPTPSENYAGQTAVVTGWGALSEGGPISDTLQEVEVPILSQEECRNSNYGE 242
            | :|:   |:.|:.           |..|||||:::|.||.:..||||.|.:...::|  :.:..
Zfish   164 RPIGVFNNDLPPLV-----------TCTVTGWGSVTENGPQASRLQEVNVTVYEPQKC--NRFYR 215

  Fly   243 SKITDNMICAGYVEQGGKDSCQGDSGGPMHVLGSGDAYQLAGIVSWGEGCAKPNAPGVYTRVGSF 307
            .|:..:||||| ..:||.|:||||||||:... .|:.|:|||:||||.||.:...|||||.:..:
Zfish   216 GKVLKSMICAG-ANEGGMDACQGDSGGPLSCF-DGERYKLAGVVSWGVGCGRAQKPGVYTTLYHY 278

  Fly   308 NDWIAENTR-----DACSCAQPEAAGEPASPMETTEQGD---QENTTANGAAEADPEVEEA 360
            ..|:..:.|     :|.|.||   .|:  :.||.....|   |..:|.|||.:.: .|.||
Zfish   279 RQWMVSSMRGELAVEADSDAQ---CGQ--AKMEPCRLPDGLAQVVSTENGAFKVE-NVSEA 333

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	79/243 (33%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	79/245 (32%)
ovch1	NP_956439.2	Tryp_SPc	56..281	CDD:214473	79/242 (33%)
		Tryp_SPc	57..281	CDD:238113	78/241 (32%)
		Tryp_SPc	331..551	CDD:238113	2/3 (67%)
		Tryp_SPc	331..549	CDD:214473	2/3 (67%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810