DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and ndl

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	NP_523947.2	Gene:	ndl / 38738	FlyBaseID:	FBgn0002926	Length:	2616	Species:	Drosophila melanogaster

Alignment Length:	291	Identity:	95/291 - (32%)
Similarity:	153/291 - (52%)	Gaps:	34/291 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 SFLDWIQSILGPEVPAEWSSPAKRECAECS---------CGNINTRHRIVGGQETEVHEYPWMIM 99
            |.:|.:..:..|  |.:...|:|....|.|         ...|....|||||..|...::|:::.
  Fly  1099 SLVDHVAYVKCP--PMQCGLPSKSSMLEHSKRVRRAVSDSKEIVGDGRIVGGSYTSALQWPFVVA 1161

  Fly   100 LMWFGNFYCGASLVNDQYALTAAHCV--NGFYHRLITVRLLEHNRQDSHVKIVDRRVSRVLIHPK 162
            :...|.|:||.::.:|::.::|||||  .|.|...:...||..:......:|  :.||.|::|..
  Fly  1162 IYRNGKFHCGGTIYSDRWIISAAHCVINYGKYFYEVRAGLLRRSSYSPATQI--QPVSHVVVHQA 1224

  Fly   163 YSTRNFDSDIALIRFNEPVRLGIDMHPVCMPTPSENYAGQ----------TAVVTGWGALSEGGP 217
            |..|:..:|::|:|...|::....:.|:|:|.......|.          ...|.||||:.|.||
  Fly  1225 YERRSMRNDLSLLRLLNPLQFNRWVKPICLPDKGRTTVGDDWIWGPVEHTLCTVVGWGAIREKGP 1289

  Fly   218 ISDTLQEVEVPILSQEECRNSNYGESKITDNMICAGYVEQGGKDSCQGDSGGPM--HVLGSGDAY 280
            .||.:::|.|||  :::|.:.   |.:.::: ||||..: ||:|:||||||||:  ..:.:.|.:
  Fly  1290 SSDPMRQVIVPI--RKKCTDP---EDQASED-ICAGDPD-GGRDACQGDSGGPLFCRSVSNPDEF 1347

  Fly   281 QLAGIVSWGEGCAKPNAPGVYTRVGSFNDWI 311
            .|||:||.|.|||:|...||||||..:.||:
  Fly  1348 YLAGVVSHGNGCARPQEFGVYTRVTLYLDWL 1378

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	85/242 (35%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	85/243 (35%)
ndl	NP_523947.2	LDLa	891..927	CDD:238060
		Tryp_SPc	1144..1377	CDD:214473	84/241 (35%)
		Tryp_SPc	1145..1379	CDD:238113	85/243 (35%)
		LDLa	1399..1430	CDD:238060
		Metaviral_G	1448..1600	CDD:118131
		LDLa	1710..1743	CDD:238060
		LDLa	1776..1811	CDD:238060
		DUF1986	2041..2158	CDD:286432
		LDLa	2309..2339	CDD:197566
		LDLa	2350..2383	CDD:197566
		LDLa	2421..2457	CDD:238060
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D380103at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.010