DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and Prss21

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	XP_006245934.1	Gene:	Prss21 / 353251	RGDID:	727870	Length:	337	Species:	Rattus norvegicus

Alignment Length:	330	Identity:	111/330 - (33%)
Similarity:	163/330 - (49%)	Gaps:	62/330 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LLILATALGDLACATPSLRSASDPEKILNNLAQLRQSSFLDWIQSILGPEVPAEWSSPAKRECAE 71
            ||::..|:.....:|.|.....||||     .:|::::.|.      ||
  Rat    11 LLVVVVAVEVTLQSTSSHVKPVDPEK-----PELQEANLLS------GP---------------- 48

  Fly    72 CSCGNINTRHRIVGGQETEVHEYPWMIMLMWFGNFYCGASLVNDQYALTAAHCV---NGFYHRLI 133
              ||:.....|||||:|.|:..:||...|..:||..|||:|:|.::.||||||.   |..:.  .
  Rat    49 --CGHRTIPSRIVGGEEAELGRWPWQGSLRVWGNHLCGATLLNRRWVLTAAHCFQKDNDPFD--W 109

  Fly   134 TVRLLEHNRQDS--HVKIVDRR--VSRVLIHPKYSTRNFDSDIALIRFNEPVRLGIDMHPVCMPT 194
            ||:..|...:.|  :::....|  :..:.:.||| |..|..||||::.:.||.....:.|:|:..
  Rat   110 TVQFGELTSRPSLWNLQAYSNRYQIEDIFLSPKY-TEQFPHDIALLKLSSPVTYSNFIQPICLLN 173

  Fly   195 PSENYAGQT-AVVTGWGALSEGG--PISDTLQEVEVPILSQEECRNSNYGESK------ITDNMI 250
            .:..:|.:| ..||||||:.|..  |:.:.||||:|.|::...|   |:...|      |..:|:
  Rat   174 STYKFANRTDCWVTGWGAIGEDESLPLPNNLQEVQVAIINNTMC---NHLFKKPDFRINIWGDMV 235

  Fly   251 CAGYVEQGGKDSC---------QGDSGGPMHVLGSGDAYQLAGIVSWGEGCAKPNAPGVYTRVGS 306
            |||..| ||||:|         |||||||: |......:...|:||||.||.:||.|||||.:..
  Rat   236 CAGSPE-GGKDACFAKLTYAAPQGDSGGPL-VCNQDTVWYQVGVVSWGIGCGRPNRPGVYTNISH 298

  Fly   307 FNDWI 311
            ..:||
  Rat   299 HYNWI 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	94/253 (37%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	95/254 (37%)
Prss21	XP_006245934.1	Tryp_SPc	57..303	CDD:214473	94/253 (37%)
Prss21	XP_006245934.1	Tryp_SPc	58..304	CDD:238113	95/254 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810