DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and OVCH2

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	XP_016873148.1	Gene:	OVCH2 / 341277	HGNCID:	29970	Length:	569	Species:	Homo sapiens

Alignment Length:	272	Identity:	90/272 - (33%)
Similarity:	134/272 - (49%)	Gaps:	36/272 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 SCGN----------INTRHRIVGGQETEVHEYPWMIMLMWFGNFYCGASLVNDQYALTAAHCV-N 126
            |||.          .|...||:||.:.|...|||.:.|.......||.|:|:.|:.:|||||: |
Human    36 SCGQSLVKVQPWNYFNIFSRILGGSQVEKGSYPWQVSLKQRQKHICGGSIVSPQWVITAAHCIAN 100

  Fly   127 GFYHRLITVRLLEHNRQDSHVKIVDRRVSRVLIHPKYSTRN-FDSDIALIRFNEPVRLGIDMHPV 190
            ......:.|...|::...:........:..|:|||.:||:. .|.||||::.....:.|..:.|:
Human   101 RNIVSTLNVTAGEYDLSQTDPGEQTLTIETVIIHPHFSTKKPMDYDIALLKMAGAFQFGHFVGPI 165

  Fly   191 CMPTPSENY-AGQTAVVTGWGALSEGGPISDTLQEVEVPILSQEEC-------RNSNYGESKITD 247
            |:|...|.: ||......|||.|:|||.:|..||||.:|||:.|||       :....|::
Human   166 CLPELREQFEAGFICTTAGWGRLTEGGVLSQVLQEVNLPILTWEECVAALLTLKRPISGKT---- 226

  Fly   248 NMICAGYVEQGGKDSCQGDSGGPMHVLGSGDAYQLAGIVSWGEGCAK----------PNAPGVYT 302
             .:|.|:.: ||:|:|||||||.:.......|:.|||:.|||.||.:          ..:||::|
Human   227 -FLCTGFPD-GGRDACQGDSGGSLMCRNKKGAWTLAGVTSWGLGCGRGWRNNVRKSDQGSPGIFT 289

  Fly   303 RVGSFNDWIAEN 314
            .:.....||.|:
Human   290 DISKVLPWIHEH 301

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	83/248 (33%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	84/250 (34%)
OVCH2	XP_016873148.1	Tryp_SPc	55..298	CDD:214473	83/248 (33%)
		Tryp_SPc	56..301	CDD:238113	84/250 (34%)
		CUB	320..424	CDD:238001
		CUB	435..546	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810